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Uridine DNA/RNA Synthesis chemical

Name: Uridine
Brand: Selleck Chemicals
SKU: S2029
Availability: InStock
Rating: 5 (8 reviews)

Cat.No.S2029

Uridine (NSC 20256,β-Uridine, Uridin) is a nucleoside, contains a uracil attached to a ribose ring via a β-N1-glycosidic bond.

Chemical Structure

Molecular Weight: 244.2

Jump to Mechanism of Action Solubility Chemical Information, Storage & Stability Specificity

Quality Control

Batch: S202901 DMSO]49 mg/mL]false]Water]49 mg/mL]false]Ethanol]Insoluble]false Purity: 99.99%

99.99

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Chemical Information, Storage & Stability

Molecular Weight	244.2	Formula	C₉H₁₂N₂O₆	Storage (From the date of receipt)	3 years-20°Cpowder
CAS No.	58-96-8	Download SDF		Storage of Stock Solutions	1 year-80°Cin solvent 1 month-20°Cin solvent
Synonyms	NSC 20256,β-Uridine, Uridin			Smiles	C1=CN(C(=O)NC1=O)C2C(C(C(O2)CO)O)O

Solubility

In vitro
Batch:

DMSO : 49 mg/mL (200.65 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)

Water : 49 mg/mL

Ethanol : Insoluble

Molarity Calculator

Mass	Concentration	Volume	Molecular Weight
=	×	×

Dilution Calculator Molecular Weight Calculator

In vivo Batch:
Homogeneous suspension	CMC-NA	≥5mg/ml	Taking the 1 mL working solution as an example, add 5 mg of this product to 1 ml of CMC-Na solution, mix evenly to obtain a homogeneous suspension with a final concentration of 5 mg/ml.
Clear solution	5%DMSO 1 40%PEG300 2 5%Tween80 3 50%ddH2O Validated by Selleck labs. Should you need adjustments to this formulation, contact our sales team for custom testing.	2.450mg/ml (10.03mM)	Taking the 1 mL working solution as an example, add 50 μL of 49 mg/ml clarified DMSO stock solution to 400 μL of PEG300, mix evenly to clarify it; add 50 μL of Tween80 to the above system, mix evenly to clarify; then continue to add 500 μL of ddH2O to adjust the volume to 1 mL. The mixed solution should be used immediately for optimal results.
Clear solution	5% DMSO 1 95% Corn oil Validated by Selleck labs. Should you need adjustments to this formulation, contact our sales team for custom testing.	1.225mg/ml (5.02mM)	Taking the 1 mL working solution as an example, add 50 μL of 24.5 mg/ml clear DMSO stock solution to 950 μL of corn oil and mix evenly. The mixed solution should be used immediately for optimal results.

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg Average weight of animals: g Dosing volume per animal:μL Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO + % + % Tween 80 + % ddH₂O

%DMSO+ %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Mechanism of Action

Clinical Trial Information

(data from https://clinicaltrials.gov, updated on 2024-05-22)

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
NCT05474105	Recruiting	Ischemic Stroke	Barts & The London NHS Trust\|Queen Mary University of London\|Nutricia Research	July 11 2023	Not Applicable
NCT05655780	Recruiting	Colorectal Neoplasms	Maastricht University Medical Center\|Maastricht University\|Wageningen University & Research\|Fontys Hogeschool\|Amsterdam UMC - Locatie AMC\|Erasmus Medical Center\|Catharina Ziekenhuis\|University of North Carolina (USA)\|Oncology patientenpanel MUMC\|Stichting Kanker.nl\|Van Weel-Bethesda Ziekenhuis\|VieCuri Medisch Centrum voor Noord-Limburg\|Gelderse Vallei Hospital\|Danone Nutricia Research\|Clinical Trial Center Maastricht B.V.\|Dutch Colorectal Cancer Group (DCCG)\|Prospectief Landelijk CRC Cohort (PLCRC)\|CRC-guideline committee\|CZ zorgverzekeraar\|Landelijke Werkgroep Diëtisten Oncologie (LWDO)	January 9 2023	--
NCT04800159	Recruiting	HIV\|Cannabis Use	University of California San Diego\|Center for Medicinal Cannabis Research	February 19 2021	Phase 2
NCT04609826	Active not recruiting	Acute Myeloid Leukemia\|Myelodysplastic Syndromes\|Chronic Myelomonocytic Leukemia	Janssen Research & Development LLC	November 26 2020	Phase 1
NCT02249468	Terminated	Mild and Moderate Alzheimer''s Disease\|Cognitively Healthy People	Danone Nutricia Research	October 2014	--

Tech Support

Handling Instructions

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