Uniconazole (S 3307D)

Catalog No.S3660 Synonyms: XE 1019D

For research use only.

Uniconazole (S 3307D, XE 1019D) is a well known inhibitor of cytochrome P450 monooxygenase that prevents the biosynthesis of trans-zeatin. Uniconazole targets CYP735As with Ki of 22 μM.

Uniconazole (S 3307D) Chemical Structure

CAS No. 83657-22-1

Selleck's Uniconazole (S 3307D) has been cited by 2 Publications

Purity & Quality Control

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Biological Activity

Description Uniconazole (S 3307D, XE 1019D) is a well known inhibitor of cytochrome P450 monooxygenase that prevents the biosynthesis of trans-zeatin. Uniconazole targets CYP735As with Ki of 22 μM.
Targets
ABA 8′-hydroxylase [1]
(Cell-free assay)
CYP735A1 [1]
(Cell-free assay)
10 nM(Ki) 22 μM(Ki)
In vitro

Uniconazole inhibits CK biosynthesis by suppressing CYP735A activity in Arabidopsis. Uniconazole inhibits the biosynthesis of gibberellin (GA), and brassinosteroid (BR) and the catabolism of abscisic acid (ABA)[1].

Protocol (from reference)

Solubility (25°C)

In vitro

DMSO 58 mg/mL
(198.77 mM)
Water Insoluble
Ethanol ''58 mg/mL

Chemical Information

Molecular Weight 291.78
Formula

C15H18ClN3O

CAS No. 83657-22-1
Storage 3 years -20°C powder
2 years -80°C in solvent
Smiles CC(C)(C)C(C(=CC1=CC=C(C=C1)Cl)N2C=NC=N2)O

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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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