Uniconazole

Catalog No.S3660 Synonyms: S 3307D, XE 1019D

Uniconazole Chemical Structure

Molecular Weight(MW): 291.78

Uniconazole is a plant growth regulator that functions by inhibiting cytochrome P450 707As (Ki = 68 nM), a family of enzymes that catabolize ABA. It suppress gibberellin and sterol biosynthesis.

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Biological Activity

Description Uniconazole is a plant growth regulator that functions by inhibiting cytochrome P450 707As (Ki = 68 nM), a family of enzymes that catabolize ABA. It suppress gibberellin and sterol biosynthesis.
Targets
ABA 8′-hydroxylase [1]
(Cell-free assay)
CYP735A1 [1]
(Cell-free assay)
10 nM(Ki) 22 μM(Ki)
In vitro

Uniconazole inhibits CK biosynthesis by suppressing CYP735A activity in Arabidopsis. Uniconazole inhibits the biosynthesis of gibberellin (GA), and brassinosteroid (BR) and the catabolism of abscisic acid (ABA)[1].

Protocol

Solubility (25°C)

In vitro DMSO 58 mg/mL (198.77 mM)
Ethanol 58 mg/mL (198.77 mM)
Water Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 291.78
Formula

C15H18ClN3O

CAS No. 83657-22-1
Storage powder
in solvent
Synonyms S 3307D, XE 1019D

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Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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P450 (e.g. CYP17) Signaling Pathway Map

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID