Spermidine

Catalog No.S3569

For research use only.

Spermidine is a natural polyamine that stimulates cytoprotective macroautophagy/autophagy.

Spermidine Chemical Structure

CAS No. 124-20-9

Selleck's Spermidine has been cited by 3 Publications

Purity & Quality Control

Choose Selective Autophagy Inhibitors

Biological Activity

Description Spermidine is a natural polyamine that stimulates cytoprotective macroautophagy/autophagy.

Protocol (from reference)

Chemical Information

Molecular Weight 145.25
Formula

C7H19N3

Density 1g/ml
CAS No. 124-20-9
Storage 2 years -20°C liquid

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Molarity Calculator

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Clinical Trial Information

NCT Number Recruitment Interventions Conditions Sponsor/Collaborators Start Date Phases
NCT05421546 Recruiting Dietary Supplement: Spermidine or Placebo COVID-19|Vaccine Reaction University of Oxford August 2022 Not Applicable
NCT04138134 Recruiting -- Venous Disease Neuromed IRCCS February 1 2022 --
NCT04823806 Recruiting Dietary Supplement: Spermidine (spermidineLIFE ®) OR Placebo Depression|Healthy University Hospital Bonn December 1 2020 Not Applicable
NCT02855918 Completed Other: Blood sample for genetic purpose Major Depression University Hospital Montpellier|Institut National de la Santé Et de la Recherche Médicale France|Sys2Diag Mixt laboratory CNRS/Alcediag Montpellier September 23 2016 Not Applicable

(data from https://clinicaltrials.gov, updated on 2022-08-01)

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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