Heme Oxygenase

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Heme Oxygenase Products

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  • New Heme Oxygenase Products
Catalog No. Product Name Information Product Use Citations Product Validations
S7880New Protoporphyrin IX Zinc Zinc Protoporphyrin (Zn(II)-protoporphyrin IX) is an potent, orally active and competitive heme oxygenase-1 (HO-1) inhibitor and significantly reduces the protective effects of Phloroglucinol (PG) against hydrogen peroxide.
S9503 Fraxetin Fraxetin (7,8-dihydroxy-6-methoxy coumarin), found in Fraxinus rhynchophylla, shows potent antioxidant activity.fraxetin alleviates lipid peroxidation, enhances hepatic antioxidant capabilities, inhibits CYP2E1 activity, and reduced the inflammatory mediators, including TNF-α and IL-1β via up-regulation of hemeoxygenase-1 (HO-1) protein.
E0526New sappanone A Sappanone A, a homoisoflavanone isolated from the heartwood of Caesalpinia sappan (Leguminosae), induces HO-1 expression by activating Nrf2 through the p38 MAPK pathway, suppresses LPS-induced NF-κB activation by suppressing the phosphorylation of RelA/p65 at Ser536, exerting its anti-inflammatory effect.
S5771 Sulforaphane Sulforaphane is a naturally occurring isothiocyanate derived from the consumption of cruciferous vegetables, such as broccoli, cabbage, and kale. It is an inducer of Nrf2. Sulforaphane is also an inhibitor of histone deacetylase (HDAC) and NF-κB. Sulforaphane increases heme oxygenase-1 (HO-1) and reduces the levels of reactive oxygen species (ROS). Sulforaphane induces cell cycle arrest and apoptosis.
Cell Mol Immunol, 2022, 19(8):872-882
Elife, 2022, 11e67368
Cell Death Discov, 2021, 7(1):375
E3438New Momordica grosvenori Extract Momordica Grosvenori Extract is extracted from Siraitia grosvenorii, which has antidiabetic effects by upregulating HO-1 and can be used for the treatment of diabetes.
S5645 Hemin Hemin (protohemin) is an iron-containing porphyrin used in the management of porphyria attacks, particularly in acute intermittent porphyria.Hemin is an Heme oxygenase (HO)-1 inducer.
Front Immunol, 2022, 13:799331
EMBO Rep, 2021, 22(2):e51162
Free Radic Biol Med, 2021, 163:234-242
S9221 Ferulaldehyde Ferulaldehyde (Coniferaldehyde, Ferulyl aldehyde) is a natural intermediate of polyphenol metabolism of intestinal microflora.
S7880New Protoporphyrin IX Zinc Zinc Protoporphyrin (Zn(II)-protoporphyrin IX) is an potent, orally active and competitive heme oxygenase-1 (HO-1) inhibitor and significantly reduces the protective effects of Phloroglucinol (PG) against hydrogen peroxide.
S9503 Fraxetin Fraxetin (7,8-dihydroxy-6-methoxy coumarin), found in Fraxinus rhynchophylla, shows potent antioxidant activity.fraxetin alleviates lipid peroxidation, enhances hepatic antioxidant capabilities, inhibits CYP2E1 activity, and reduced the inflammatory mediators, including TNF-α and IL-1β via up-regulation of hemeoxygenase-1 (HO-1) protein.
E0526New sappanone A Sappanone A, a homoisoflavanone isolated from the heartwood of Caesalpinia sappan (Leguminosae), induces HO-1 expression by activating Nrf2 through the p38 MAPK pathway, suppresses LPS-induced NF-κB activation by suppressing the phosphorylation of RelA/p65 at Ser536, exerting its anti-inflammatory effect.
S5771 Sulforaphane Sulforaphane is a naturally occurring isothiocyanate derived from the consumption of cruciferous vegetables, such as broccoli, cabbage, and kale. It is an inducer of Nrf2. Sulforaphane is also an inhibitor of histone deacetylase (HDAC) and NF-κB. Sulforaphane increases heme oxygenase-1 (HO-1) and reduces the levels of reactive oxygen species (ROS). Sulforaphane induces cell cycle arrest and apoptosis.
Cell Mol Immunol, 2022, 19(8):872-882
Elife, 2022, 11e67368
Cell Death Discov, 2021, 7(1):375
E3438New Momordica grosvenori Extract Momordica Grosvenori Extract is extracted from Siraitia grosvenorii, which has antidiabetic effects by upregulating HO-1 and can be used for the treatment of diabetes.
S7880New Protoporphyrin IX Zinc Zinc Protoporphyrin (Zn(II)-protoporphyrin IX) is an potent, orally active and competitive heme oxygenase-1 (HO-1) inhibitor and significantly reduces the protective effects of Phloroglucinol (PG) against hydrogen peroxide.
E0526New sappanone A Sappanone A, a homoisoflavanone isolated from the heartwood of Caesalpinia sappan (Leguminosae), induces HO-1 expression by activating Nrf2 through the p38 MAPK pathway, suppresses LPS-induced NF-κB activation by suppressing the phosphorylation of RelA/p65 at Ser536, exerting its anti-inflammatory effect.
E3438New Momordica grosvenori Extract Momordica Grosvenori Extract is extracted from Siraitia grosvenorii, which has antidiabetic effects by upregulating HO-1 and can be used for the treatment of diabetes.
Tags: Heme Oxygenase inhibitor|Heme Oxygenase agonist|Heme Oxygenase activator|Heme Oxygenase inducer|Heme Oxygenase antagonist|Heme Oxygenase signaling pathway|Heme Oxygenase assay kit