cGAS antagonist | cGAS inhibitor | cGAS agonist

You can personalize your library with chemicals from within Selleck's inventory. Build the right library for your research endeavors by choosing from compounds in all of our available libraries.

Please contact us at [email protected] to customize your library.

You could select:

Specific Compounds Quantities 96 or 384 well Plate Map Dry/solid or DMSO solution

Antibodies

in vivo Antibodies

Biosimilar Antibodies

Bioreagents

qPCR: 2x SYBR Green qPCR Master Mix; 2x SYBR Green qPCR Master Mix(Low ROX); 2x SYBR Green qPCR Master Mix(High ROX)

Protein Assay: Protein A/G Magnetic Beads for IP; Anti-Flag magnetic beads; Anti-Flag Affinity Gel; Anti-Myc magnetic beads; Anti-HA magnetic beads; Poly FLAG Peptide lyophilized powder

Protease Inhibitor Cocktail: Protease Inhibitor Cocktail (EDTA-Free, 100X in DMSO); Phosphatase Inhibitor Cocktail (2 Tubes, 100X)

Cell Biology: Cell Counting Kit-8 (CCK-8)

Animal Experiment: Mouse Direct PCR Kit (For Genotyping)

New Products

Contact Us

Headquarters

Worldwide Distributors

Catalog No.	Product Name	Information	Product Use Citations
S6841	RU.521	RU.521 (RU320521) is an active, potent and selective inhibitor of cyclic GMP-AMP synthase (cGAS) that inhibits the cGAS-mediated signaling with IC50 of 700 nM. RU.521 binds to the cGAS/dsDNA complex with Kd of 36.2 nM.	Cancer Lett, 2024, 586:216695 Phytomedicine, 2023, 120:155020 iScience, 2023, 26(10):107792
S8944	G150	G150 is a potent and highly selective human cyclic GMP-AMP synthase (cGAS) inhibitor with IC50 of 10.2 nM.	J Leukoc Biol, 2022, 10.1002/JLB.4MA0422-616R
S9615	PF-06928215	PF-06928215 is a high affinity inhibitor of cyclic GMP-AMP synthase (cGAS) with an IC50 of 4.9 μM.
S0775	IRAK4-IN-4	IRAK4-IN-4 (compound 15) is an inhibitor of interleukin-1 receptor–associated kinase 4 (IRAK4) and cyclic GMP-AMP synthase (cGAS) with IC50 of 2.8 nM and 2.1 nM, respectively.
S9945	G140	G140 is a potent and selective inhibitor of cyclic GMP-AMP synthase (cGAS), with IC50s of 14.0 nM and 442 nM for h-cGAS and m-cGAS, respectively.
S6841	RU.521	RU.521 (RU320521) is an active, potent and selective inhibitor of cyclic GMP-AMP synthase (cGAS) that inhibits the cGAS-mediated signaling with IC50 of 700 nM. RU.521 binds to the cGAS/dsDNA complex with Kd of 36.2 nM.	Cancer Lett, 2024, 586:216695 Phytomedicine, 2023, 120:155020 iScience, 2023, 26(10):107792
S8944	G150	G150 is a potent and highly selective human cyclic GMP-AMP synthase (cGAS) inhibitor with IC50 of 10.2 nM.	J Leukoc Biol, 2022, 10.1002/JLB.4MA0422-616R
S9615	PF-06928215	PF-06928215 is a high affinity inhibitor of cyclic GMP-AMP synthase (cGAS) with an IC50 of 4.9 μM.
S0775	IRAK4-IN-4	IRAK4-IN-4 (compound 15) is an inhibitor of interleukin-1 receptor–associated kinase 4 (IRAK4) and cyclic GMP-AMP synthase (cGAS) with IC50 of 2.8 nM and 2.1 nM, respectively.
S9945	G140	G140 is a potent and selective inhibitor of cyclic GMP-AMP synthase (cGAS), with IC50s of 14.0 nM and 442 nM for h-cGAS and m-cGAS, respectively.

cGAS

cGAS Products

Choose Selective cGAS Inhibitors