Home Cytoskeletal Signaling Kinesin inhibitor SB-743921

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SB-743921 Kinesin inhibitor

Cat.No.E4595

SB-743921 (SB-921) is an inhibitor of Kinesin Spindle Protein (KSP), a mitotic protein essential for cell cycle control and motility. It functions by selectively targeting rapidly dividing cells and disrupting spindle formation during cell division, leading to G2/M phase arrest and ultimately causing cell death. It also inhibits proliferation and induces apoptosis in diffuse large B-cell lymphoma (DLBCL) cell lines.
SB-743921 Kinesin inhibitor Chemical Structure

Chemical Structure

Molecular Weight: 553.52

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Chemical Information, Storage & Stability

Molecular Weight 553.52 Formula

C31H33ClN2O3.ClH

 Storage (From the date of receipt)
CAS No. 618430-39-0 Download SDF Storage of Stock Solutions

Mechanism of Action

Targets/IC50/Ki
Kinesin
References

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