For research use only.
Catalog No.S4948 Synonyms: Rubraca, AG014699, PF01367338
CAS No. 283173-50-2
Rucaparib (Rubraca, AG014699, PF01367338) is an inhibitor of PARP with Ki of 1.4 nM for PARP1 in a cell-free assay, also showing binding affinity to eight other PARP domains.
Selleck's Rucaparib has been cited by 10 publications
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Choose Selective PARP Inhibitors
|Description||Rucaparib (Rubraca, AG014699, PF01367338) is an inhibitor of PARP with Ki of 1.4 nM for PARP1 in a cell-free assay, also showing binding affinity to eight other PARP domains.|
|In vitro||DMSO||65 mg/mL (201.01 mM)|
|Synonyms||Rubraca, AG014699, PF01367338|
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Clinical Trial Information
|NCT Number||Recruitment||interventions||Conditions||Sponsor/Collaborators||Start Date||Phases|
|NCT04539327||Recruiting||Drug: Rucaparib||Epithelial Ovarian Cancer|Fallopian Tube Cancer|Primary Peritoneal Cancer||Grupo Español de Investigación en Cáncer de Ovario|Clovis Oncology Inc.||July 29 2020||--|
|NCT04179396||Active not recruiting||Drug: Rucaparib|Drug: Enzalutamide|Drug: Abiraterone||Metastatic Castration Resistant Prostate Cancer||Clovis Oncology Inc.||December 5 2019||Phase 1|
|NCT04171700||Recruiting||Drug: Rucaparib||Solid Tumor||Clovis Oncology Inc.||November 21 2019||Phase 2|
|NCT03824704||Terminated||Drug: Rucaparib|Drug: Nivolumab||Epithelial Ovarian Cancer|Fallopian Tube Cancer|Primary Peritoneal Carcinoma|High Grade Serous Carcinoma|Endometrioid Adenocarcinoma||Clovis Oncology Inc.|Bristol-Myers Squibb|Foundation Medicine||August 23 2019||Phase 2|
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