CAS No. 53-60-1
Batch:
Purity:99.13
Chemical Structure
Check the
Promazine hydrochloride
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 53-60-1 | |
|---|---|---|
| Molecular Formula |
C17H20N2S.HCl |
|
| Molecular Weight (MW) | 320.88 | |
| SMILES | CN(C)CCCN1C2=CC=CC=C2SC3=CC=CC=C31.Cl |
Promazine hydrochloride is a phenothiazine-class antagonist targeting dopamine D1, D2, and D4 receptors, serotonin 5-HT2A and 5-HT2C receptors, muscarinic acetylcholine receptors (M1–M5), alpha-1 adrenergic receptors, and histamine H1 receptors. By blocking these neuroreceptors, it modulates dopaminergic, serotonergic, and cholinergic signaling pathways, leading to altered neurotransmitter-mediated downstream responses and cellular signaling events involved in central nervous system function.
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Concentration
Volume
Mass
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Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
64 mg/mL
(199.45 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
- Promazine hydrochloride Solubility in DMSO
- Promazine hydrochloride Stock Solution
- Promazine hydrochloride Storage
- Promazine hydrochloride Stability
- Promazine hydrochloride Molecular Weight
- Promazine hydrochloride SMILES
- Promazine hydrochloride Chemical Structure (2D and 3D)
- Promazine hydrochloride SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.