Phorbol 12-myristate 13-acetate (PMA)

Catalog No.S7791

Phorbol 12-myristate 13-acetate (PMA) Chemical Structure

Molecular Weight(MW): 616.83

Phorbol 12-myristate 13-acetate (PMA), a potent activator of PKC, is active at nanomolar concentrations.

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USD 357 In stock
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Biological Activity

Description Phorbol 12-myristate 13-acetate (PMA), a potent activator of PKC, is active at nanomolar concentrations.

Protocol

References

Solubility (25°C)

In vitro DMSO 100 mg/mL (162.11 mM)
Ethanol 100 mg/mL (162.11 mM)
Water Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 616.83
Formula

C36H56O8

CAS No. 16561-29-8
Storage powder
in solvent
Synonyms N/A

Bio Calculators

Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass
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*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

  • C1
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    C2
    V2

* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).

The Serial Dilution Calculator Equation

  • Serial Dilutions

  • Computed Result

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):
Molecular Weight Calculator

Molecular Weight Calculator

Enter the chemical formula of a compound to calculate its molar mass and elemental composition:

Total Molecular Weight: g/mol

Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2

Instructions to calculate molar mass (molecular weight) of a chemical compound:

To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.

Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT04075123 Not yet recruiting Other: CPAP Respiratory Insufficiency Syndrome of Newborn Canadian Neonatal Network|MOUNT SINAI HOSPITAL October 1 2019 --
NCT03253263 Recruiting Drug: SHP607 Retinopathy of Prematurity (ROP)|Intraventricular Hemorrhage|Bronchopulmonary Dysplasia|Chronic Lung Disease of Prematurity Shire May 9 2019 Phase 2
NCT03782610 Recruiting -- Patent Ductus Arteriosus|Preterm Infant|Bronchopulmonary Dysplasia|Neurodevelopmental Abnormality Nationwide Children''s Hospital|National Heart Lung and Blood Institute (NHLBI)|Ohio State University|OhioHealth|Mount Carmel Health System April 1 2019 --
NCT03340727 Recruiting Drug: Caffeine Citrate|Drug: Placebo Apnea of Prematurity NICHD Neonatal Research Network|Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) February 27 2019 Phase 3
NCT03321734 Recruiting Drug: Caffeine|Drug: Placebos Intermittent Hypoxia Children''s Research Institute|Boston University|Beth Israel Medical Center|University of Massachusetts Worcester|American SIDS Institute|Walter Reed National Military Medical Center|Dartmouth-Hitchcock Medical Center|Children''s Hospital of Philadelphia|Johns Hopkins All Children''s Hospital|Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) January 18 2019 Phase 2

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3

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PKC Signaling Pathway Map

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID