Optovin

Catalog No.S8073

Optovin Chemical Structure

Molecular Weight(MW): 315.41

Optovin is a reversible photoactivated TRPA1 activator.

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Biological Activity

Description Optovin is a reversible photoactivated TRPA1 activator.
Targets
TRPA1 [1]
In vitro

Optovin activates human TRPA1 via structure dependent photochemical reactions. [1]

In vivo Optovin enables real-time optical control of neurons, and also elicits nociceptive behaviors in adult mice. In animals with severed spinal cords, optovin treatment enables control of motor activity in the paralyzed extremities by localized illumination. [1]

Protocol

Animal Research:[1]
+ Expand
  • Animal Models: Zebrafish and mice
  • Formulation: DMSO
  • Dosages: 50 μM (Zebrafish); 15 mM (mice)
  • Administration: Treated on the ear (mice); Embryos are incubated in Optovin solution (Zebrafish )
    (Only for Reference)

Solubility (25°C)

In vitro DMSO 63 mg/mL warmed (199.74 mM)
Water Insoluble
Ethanol Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 315.41
Formula

C15H13N3OS2

CAS No. 348575-88-2
Storage powder
in solvent
Synonyms N/A

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Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3

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