Guaiacol

Catalog No.S3872 Synonyms: o-methoxyphenol, 2-hydroxyanisole, O-methylcatechol

For research use only.

Guaiacol (O-methoxyphenol, 2-hydroxyanisole, O-methylcatechol) is a phenolic natural product first isolated from Guaiac resin and the oxidation of lignin. It is a precursor to various flavorants, such as eugenoland vanillin. Guaiacol, a phenolic compound isolated from Guaiac resin, inhibits LPS-stimulated COX-2 expression and NF-κB activation. Anti-inflammatory activity.

Guaiacol Chemical Structure

CAS No. 90-05-1

Purity & Quality Control

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Biological Activity

Description Guaiacol (O-methoxyphenol, 2-hydroxyanisole, O-methylcatechol) is a phenolic natural product first isolated from Guaiac resin and the oxidation of lignin. It is a precursor to various flavorants, such as eugenoland vanillin. Guaiacol, a phenolic compound isolated from Guaiac resin, inhibits LPS-stimulated COX-2 expression and NF-κB activation. Anti-inflammatory activity.
Targets
NF-κB [1]
()
COX-2 [1]
()

Protocol (from reference)

Solubility (25°C)

In vitro

DMSO 24 mg/mL
(193.33 mM)


Chemical Information

Molecular Weight 124.14
Formula

C7H8O2

CAS No. 90-05-1
Storage 3 years -20°C powder
2 years -80°C in solvent
Smiles COC1=CC=CC=C1O

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Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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