NOD1
Signaling Pathway Map
Research Area
- Inhibitory Selectivity
- Solubility
| Catalog No. | Product Name | Solubility(25°C) | ||
|---|---|---|---|---|
| Water | DMSO | Alcohol | ||
| S2863 | ML130 (Nodinitib-1) | <1 mg/mL | 57 mg/mL | 2 mg/mL |
Isoform-specific Inhibitors
- NOD1 Inhibitors (1)
| Catalog No. | Information | Product Use Citations | Product Validations |
|---|---|---|---|
| S2863 |
ML130 (Nodinitib-1)ML130 (Nodinitib-1) is a potent and selective inhibitor of NOD1 with IC50 of 0.56 μM, inhibits NF-κB activation, exhibits 36-fold selectivity over NOD2. |
(E) Gentamicin protection assay performed as in (B) with healthy control MDM (n=4). Quantification of S. typhimurium-CFU after inhibition of NOD1 with ML-130 and MDP pre-stimulation. |
