Dazoxiben hydrochloride

Catalog No.S0541 Synonyms: Dazoxiben HCl

For research use only.

Dazoxiben hydrochloride (HCl) is a potent, selevtive and orally active inhibitor of thromboxane (TX) synthase. Dazoxiben inhibits TXB2 production in clotting human whole blood with IC50 of 0.3 μM and causes parallel enhancement of PGE2 production.

Dazoxiben hydrochloride Chemical Structure

CAS No. 74226-22-5

Purity & Quality Control

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Biological Activity

Description Dazoxiben hydrochloride (HCl) is a potent, selevtive and orally active inhibitor of thromboxane (TX) synthase. Dazoxiben inhibits TXB2 production in clotting human whole blood with IC50 of 0.3 μM and causes parallel enhancement of PGE2 production.
Targets
PGE2 [1] TXB2 [1]
(Cell-free assay)
0.3 μM

Protocol (from reference)

Solubility (25°C)

In vitro

Chemical Information

Molecular Weight 268.7
Formula

C12H13ClN2O3

CAS No. 74226-22-5
Storage 3 years -20°C powder
2 years -80°C in solvent
Smiles C1=CC(=CC=C1C(=O)O)OCCN2C=CN=C2.Cl

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Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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