Home DNA Damage/DNA Repair DNA/RNA Synthesis chemical 2’-deoxyuridine

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2’-deoxyuridine DNA/RNA Synthesis chemical

Cat.No.S5505

2'-deoxyuridine (dU, 2'-dU) is frequently halogenated to create thymidine analogues useful for studies of DNA synthesis and degradation mechanisms.
2’-deoxyuridine DNA/RNA Synthesis chemical Chemical Structure

Chemical Structure

Molecular Weight: 228.20

Jump to Mechanism of Action Solubility Chemical Information, Storage & Stability Specificity

Quality Control

Batch: S550501 DMSO]45 mg/mL]false]]]false]]]false Purity: 99.98%
99.98

Chemical Information, Storage & Stability

Molecular Weight 228.20 Formula

C9H12N2O5

 Storage (From the date of receipt) 3 years -20°C powder
CAS No. 951-78-0 -- Storage of Stock Solutions

Synonyms dU, 2'-dU Smiles C1C(C(OC1N2C=CC(=O)NC2=O)CO)O

Solubility

In vitro
Batch:

DMSO : 45 mg/mL (197.19 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)

Molarity Calculator

Mass Concentration Volume Molecular Weight

In vivo
Batch:

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg
g
μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO
%
% Tween 80
% ddH2O
% DMSO
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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Mechanism of Action

Clinical Trial Information

(data from https://clinicaltrials.gov, updated on 2024-05-22)

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT03866954 Withdrawn
Mitochondrial Diseases|Metabolic Disease|Inborn Errors of Metabolism
St George''s University of London|Neovii Biotech
 November 2024 Phase 2
NCT06380426 Not yet recruiting
Monogenic Obesity
Assistance Publique - Hôpitaux de Paris
 July 1 2024 --
NCT06391723 Not yet recruiting
Major Depressive Disorder
Centre Hospitalier du Rouvray|University Hospital Rouen|Centre Hospitalier Sainte Anne Paris
 June 2024 Not Applicable
NCT06393829 Not yet recruiting
Cardiovascular Diseases
Centre for Interdisciplinary Research in Rehabilitation of Greater Montreal|Jewish General Hospital
 June 1 2024 Not Applicable

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