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2’-deoxyuridine

Name: 2’-deoxyuridine
Brand: Selleck Chemicals
SKU: S5505
Rating: 5 (1 reviews)

Synonyms: dU, 2'-dU

Catalog No.S5505 Purity: 99.98%

2'-deoxyuridine (dU, 2'-dU) is frequently halogenated to create thymidine analogues useful for studies of DNA synthesis and degradation mechanisms.

2’-deoxyuridine Chemical Structure

CAS: 951-78-0

Purity & Quality Control

Batch: S550501 DMSO] 45 mg/mL] false] ] ] false] ] ] false Purity: 99.98%

99.98

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Signaling Pathway

DNA/RNA Synthesis Signaling Pathway

Choose Selective DNA/RNA Synthesis Inhibitors

Biological Activity

Description	2'-deoxyuridine (dU, 2'-dU) is frequently halogenated to create thymidine analogues useful for studies of DNA synthesis and degradation mechanisms.

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
Clinical Trial Information (data from https://clinicaltrials.gov, updated on 2024-01-11)
NCT03866954	Withdrawn	Mitochondrial Diseases\|Metabolic Disease\|Inborn Errors of Metabolism	St George''s University of London\|Neovii Biotech	November 2024	Phase 2
NCT05703763	Not yet recruiting	Giant Cell Arteritis	Hopital du Sacre-Coeur de Montreal	March 2024	--
NCT06185491	Not yet recruiting	Diabetes Mellitus	Nantes University Hospital	March 2024	Not Applicable
NCT06078384	Not yet recruiting	Triple-negative Breast Cancer	UNICANCER\|MSD France\|Vall d''Hebron Institute of Oncology\|SOLTI Breast Cancer Research Group	February 1 2024	Phase 2

Chemical Information & Solubility

Molecular Weight	228.20	Formula	C₉H₁₂N₂O₅
CAS No.	951-78-0	SDF	--
Smiles	C1C(C(OC1N2C=CC(=O)NC2=O)CO)O
Storage (From the date of receipt)	3 years -20°C powder	Storage of Stock Solutions Aliquot the stock solutions to avoid repeated freeze-thaw cycles	1 year-80°Cin solvent
Storage (From the date of receipt)	3 years -20°C powder		1 month-20°Cin solvent

In vitro
Batch:

DMSO : 45 mg/mL ( (197.19 mM)； Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.

In vivo Formulation Calculator

Preparing Stock Solutions

Molarity Calculator

Dilution Calculator Molecular Weight Calculator

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg Average weight of animals: g Dosing volume per animal:μL Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO + % + % Tween 80 + % ddH₂O

%DMSO+ %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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