For research use only.
Catalog No.S5899 Synonyms: (R)-Ibuprofen
CAS No. 51146-57-7
(R)-(-)-Ibuprofen ((R)-Ibuprofen) inhibits the activation of NF-κB in response to T-cell stimulation with IC50 of 121.8 μM. R(-)-ibuprofen exerts anti-inflammatory and antinociceptive effects.
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Choose Selective NF-κB Inhibitors
|Description||(R)-(-)-Ibuprofen ((R)-Ibuprofen) inhibits the activation of NF-κB in response to T-cell stimulation with IC50 of 121.8 μM. R(-)-ibuprofen exerts anti-inflammatory and antinociceptive effects.|
|In vitro||DMSO||41 mg/mL (198.75 mM)|
|Water||41 mg/mL (198.75 mM)|
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|Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)|
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|% DMSO % % Tween 80 % ddH2O|
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Clinical Trial Information
|NCT Number||Recruitment||interventions||Conditions||Sponsor/Collaborators||Start Date||Phases|
|NCT05013567||Not yet recruiting||Drug: Ibuprofen gel|Other: Placebo||Musculoskeletal Pain|Acute Pain|Stretch|Sprains||Brainfarma Industria Química e Farmacêutica S/A||March 2022||Phase 3|
|NCT04986839||Not yet recruiting||Drug: Paracetamol injection|Drug: Ibuprofen injection||Patent Ductus Arteriosus||Manchester University NHS Foundation Trust||October 1 2021||Phase 2|Phase 3|
|NCT05030324||Not yet recruiting||Drug: XC221 100 mg|Drug: XC221 200 mg|Drug: Placebo||Influenza|Viral Respiratory Infection|Acute Viral Upper Respiratory Infections||Valenta Pharm JSC||September 2021||Phase 2|
|NCT04942015||Not yet recruiting||Drug: Honghuaruyi Wan|Drug: Placebo of Honghuaruyi Wan||Endometriosis|Dysmenorrhea||Beijing University of Chinese Medicine||June 21 2021||Phase 4|
|NCT04723394||Active not recruiting||Drug: AZD7442|Drug: Placebo||COVID-19||AstraZeneca||January 28 2021||Phase 3|
Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.
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