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RAAS

Other Endocrinology & Hormones Related Inhibitors

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Isoform-selective Products

Cat.No. Product Name Information Product Use Citations Product Validations
S2051 Captopril Captopril (SQ 14225,Capoten) is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 6 nM.
Nat Commun, 2025, 16(1):7347
J Neuroinflammation, 2025, 22(1):121
Toxicol Appl Pharmacol, 2025, 500:117375
S2099 Temocapril HCl Temocapril HCl (CS-622) is the hydrochloride of Temocapril, which is a long-acting angiotensin-converting enzyme (ACE) inhibitor, used for the treatment of hypertension.
J Immunother Cancer, 2024, 12(11)e009805
J Pers Med, 2022, 12(2)258
Hum Cell, 2022, 10.1007/s13577-022-00671-y
S1657 Enalaprilat Dihydrate Enalaprilat (MK-422) is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 1.94 nM.
J Immunother Cancer, 2024, 12(11)e009805
J Transl Med, 2021, 19(1):91
Biomolecules, 2021, 11(9)1370
S1941 Enalapril Maleate Enalapril (MK-421) Maleate is an angiotensin-converting enzyme (ACE) inhibitor, used in the treatment of hypertension, diabetic nephropathy, and chronic heart failure.
J Immunother Cancer, 2024, 12(11)e009805
BMC Pharmacol Toxicol, 2024, 25(1):25
Molecules, 2022, 27(4)1417
S2199 Aliskiren Hemifumarate Aliskiren hemifumarate(CGP 60536 hemifumarate, CGP60536B hemifumarate, SPP 100 hemifumarate) is a direct renin inhibitor with IC50 of 1.5 nM.
J Immunother Cancer, 2024, 12(11)e009805
Kidney Int, 2018, 94(4):689-700
J Physiol, 2018, 596(15):3217-3232
S1284 Benazepril HCl Benazepril HCl (CGS 14824A) is a novel angiotensin I converting enzyme inhibitor, used primarily in treatment of hypertension.
J Immunother Cancer, 2024, 12(11)e009805
Exp Ther Med, 2021, 22(4):1082
Mol Pharm, 2015, 12(9):3399-407
S5767 Aliskiren Aliskiren(CGP 60536) is a renin inhibitor with antihypertensive activity.
Front Pharmacol, 2025, 16:1539032
Angiogenesis, 2017, 20(1):175-181
Am J Physiol Heart Circ Physiol, 2016, 311(3):H849-54
S1506 Perindopril Erbumine Perindopril Erbumine (S9490-3) is a pro-drug and metabolized in vivo by hydrolysis of the ester group to form Perindoprilat, the biologically active metabolite, a potent ACE inhibitor with IC50 of 1.05 nM. This compound is used for in vivo studies and Perindoprilat is recommened for in vitro research.
J Immunother Cancer, 2024, 12(11)e009805
Neurotherapeutics, 2018, 15(2):500-510
S7382 Phosphoramidon Disodium Salt Phosphoramidon Disodium Salt is a metalloendopeptidase inhibitor, widely used as a biochemical tool. Phosphoramidon inhibited ECE, NEP, and ACE activities with IC50 values of 3.5 μM, 0.034 μM, and 78 μM, respectively.
Diagnostics, 2022, 12(11)
Diagnostics (Basel), 2022, 12(11)2710
S1793 Ramipril Ramipril (HOE-498) is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 5 nM.
J Immunother Cancer, 2024, 12(11)e009805

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