Mineralocorticoid Receptor Inhibitors/Antagonists

Mineralocorticoid Receptor Products

All (5)
Mineralocorticoid Receptor Inhibitor (1)
Mineralocorticoid Receptor Antagonists (4)
New Mineralocorticoid Receptor Products

Cat.No.	Product Name	Information	Product Use Citations
S1707	Eplerenone	Eplerenone is a mineralocorticoid receptor antagonist, and blocks the action of aldosterone, used to control high blood pressure.	J Immunother Cancer, 2024, 12(11)e009805 Acta Pharm Sin B, 2023, 13(2):662-677 Oncol Rep, 2021, 46(3)202
E1239	Apararenone	Apararenone (MT-3995) is a selective, long-acting nonsteroidal mineralocorticoid receptors (MR) antagonist.
S5273	Canrenone	Canrenone (Aldadiene, SC-9376, RP-11614, 6,7-Dehydro-7α-desthioacetylspironolactone), a cardiovascular drug, a sort of steroid, is spironolactone's major metabolite and has been widely used as a nonselective aldosterone receptor antagonist clinically to treat heart failure, high blood pressure, edema, liver ascites, and other cardiovascular diseases.
S9702	Finerenone (BAY 94-8862)	Finerenone (FIN, BAY 94-8862) is a highly selective and orally available nonsteroidal antagonist of mineralocorticoid receptor (MR) with IC50 of 18 nM. Finerenone has the potential for cardiorenal diseases research, such as type 2 diabetes mellitus and chronic kidney disease.
E0704	Esaxerenone (CS-3150)	Esaxerenone (CS-3150), a selective nonsteroidal mineralocorticoid receptor (MR) antagonist, binds to mineralocorticoid receptor and inhibits (3)H-aldosterone binding to mineralocorticoid receptor with an IC50 value of 9.4 nM. This compound also has the property of increasing the likelihood of albuminuria returning to normal levels and reducing progression of albuminuria to higher levels.
E0704	Esaxerenone (CS-3150)	Esaxerenone (CS-3150), a selective nonsteroidal mineralocorticoid receptor (MR) antagonist, binds to mineralocorticoid receptor and inhibits (3)H-aldosterone binding to mineralocorticoid receptor with an IC50 value of 9.4 nM. This compound also has the property of increasing the likelihood of albuminuria returning to normal levels and reducing progression of albuminuria to higher levels.
S1707	Eplerenone	Eplerenone is a mineralocorticoid receptor antagonist, and blocks the action of aldosterone, used to control high blood pressure.	J Immunother Cancer, 2024, 12(11)e009805 Acta Pharm Sin B, 2023, 13(2):662-677 Oncol Rep, 2021, 46(3)202
E1239	Apararenone	Apararenone (MT-3995) is a selective, long-acting nonsteroidal mineralocorticoid receptors (MR) antagonist.
S5273	Canrenone	Canrenone (Aldadiene, SC-9376, RP-11614, 6,7-Dehydro-7α-desthioacetylspironolactone), a cardiovascular drug, a sort of steroid, is spironolactone's major metabolite and has been widely used as a nonselective aldosterone receptor antagonist clinically to treat heart failure, high blood pressure, edema, liver ascites, and other cardiovascular diseases.
S9702	Finerenone (BAY 94-8862)	Finerenone (FIN, BAY 94-8862) is a highly selective and orally available nonsteroidal antagonist of mineralocorticoid receptor (MR) with IC50 of 18 nM. Finerenone has the potential for cardiorenal diseases research, such as type 2 diabetes mellitus and chronic kidney disease.