Mineralocorticoid Receptor

Inhibitory Selectivity

Mineralocorticoid Receptor Products

All (3) Mineralocorticoid Receptor Antagonists (3)

Catalog No.	Information	Product Use Citations
S1707	Eplerenone (CGP 30083) Eplerenone (CGP 30083, SC-66110) is a mineralocorticoid receptor antagonist, and blocks the action of aldosterone, used to control high blood pressure.	Oncol Rep, 2021, 46(3)202 BMJ Open Diabetes Res Care, 2020, Int J Mol Sci, 2019, 20(4)
S5273	Canrenone Canrenone (Aldadiene, SC-9376, RP-11614, 6,7-Dehydro-7α-desthioacetylspironolactone), a cardiovascular drug, a sort of steroid, is spironolactone's major metabolite and has been widely used as a nonselective aldosterone receptor antagonist clinically to treat heart failure, high blood pressure, edema, liver ascites, and other cardiovascular diseases.
S9702	Finerenone Finerenone (FIN, BAY 94-8862) is a highly selective and orally available nonsteroidal antagonist of mineralocorticoid receptor (MR) with IC50 of 18 nM. Finerenone has the potential for cardiorenal diseases research, such as type 2 diabetes mellitus and chronic kidney disease.

Catalog No.

Information

Product Use Citations

Product Validations

S1707

Eplerenone (CGP 30083)

Eplerenone (CGP 30083, SC-66110) is a mineralocorticoid receptor antagonist, and blocks the action of aldosterone, used to control high blood pressure.

Oncol Rep, 2021, 46(3)202

BMJ Open Diabetes Res Care, 2020,

Int J Mol Sci, 2019, 20(4)

S5273

Canrenone (Aldadiene, SC-9376, RP-11614, 6,7-Dehydro-7α-desthioacetylspironolactone), a cardiovascular drug, a sort of steroid, is spironolactone's major metabolite and has been widely used as a nonselective aldosterone receptor antagonist clinically to treat heart failure, high blood pressure, edema, liver ascites, and other cardiovascular diseases.

S9702

Finerenone

Finerenone (FIN, BAY 94-8862) is a highly selective and orally available nonsteroidal antagonist of mineralocorticoid receptor (MR) with IC50 of 18 nM. Finerenone has the potential for cardiorenal diseases research, such as type 2 diabetes mellitus and chronic kidney disease.

Catalog No.	Information	Product Use Citations
S1707	Eplerenone (CGP 30083) Eplerenone (CGP 30083, SC-66110) is a mineralocorticoid receptor antagonist, and blocks the action of aldosterone, used to control high blood pressure.	Oncol Rep, 2021, 46(3)202 BMJ Open Diabetes Res Care, 2020, Int J Mol Sci, 2019, 20(4)
S5273	Canrenone Canrenone (Aldadiene, SC-9376, RP-11614, 6,7-Dehydro-7α-desthioacetylspironolactone), a cardiovascular drug, a sort of steroid, is spironolactone's major metabolite and has been widely used as a nonselective aldosterone receptor antagonist clinically to treat heart failure, high blood pressure, edema, liver ascites, and other cardiovascular diseases.
S9702	Finerenone Finerenone (FIN, BAY 94-8862) is a highly selective and orally available nonsteroidal antagonist of mineralocorticoid receptor (MR) with IC50 of 18 nM. Finerenone has the potential for cardiorenal diseases research, such as type 2 diabetes mellitus and chronic kidney disease.