Captopril

Catalog No.S2051 Synonyms: SQ 14225,Capoten

For research use only.

Captopril (SQ 14225,Capoten) is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 6 nM.

Captopril Chemical Structure

CAS No. 62571-86-2

Selleck's Captopril has been cited by 5 Publications

Purity & Quality Control

Choose Selective RAAS Inhibitors

Other RAAS Products

Biological Activity

Description Captopril (SQ 14225,Capoten) is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 6 nM.
Targets
ACE [1]
6 nM

Protocol (from reference)

Solubility (25°C)

In vitro

Chemical Information

Molecular Weight 217.29
Formula

C9H15NO3S

CAS No. 62571-86-2
Storage 3 years -20°C powder
2 years -80°C in solvent
Smiles CC(CS)C(=O)N1CCCC1C(=O)O

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Clinical Trial Information

NCT Number Recruitment Interventions Conditions Sponsor/Collaborators Start Date Phases
NCT04964050 Not yet recruiting Drug: Capozide|Drug: ACE-Hemmer-Ratiopharm Healthy Volunteers GlaxoSmithKline April 21 2022 Phase 1
NCT04878315 Not yet recruiting Drug: Capoten|Drug: Captopril Healthy Volunteers GlaxoSmithKline December 10 2021 Phase 1
NCT04355429 Unknown status Drug: captopril 25mg Pneumonia|Coronavirus Infection|COVID-19 Assistance Publique - Hôpitaux de Paris May 5 2020 Phase 2
NCT04224675 Not yet recruiting Drug: Atenolol Aneurysm Onassis Cardiac Surgery Centre March 7 2020 Not Applicable
NCT03660293 Completed Drug: Atorvastatin|Drug: Captopril|Drug: L-carnitine Diabetes Mellitus Type 1 Tanta University April 1 2017 Not Applicable

(data from https://clinicaltrials.gov, updated on 2022-08-01)

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3
If you have any other enquiries, please leave a message.

* Indicates a Required Field

Please enter your name.
Please enter your email. Please enter a valid email address.
Please write something to us.
Tags: buy Captopril | Captopril supplier | purchase Captopril | Captopril cost | Captopril manufacturer | order Captopril | Captopril distributor