Metoclopramide HCl

Catalog No.S4289

Metoclopramide HCl Chemical Structure

Molecular Weight(MW): 336.26

Metoclopramide HCl is a selective dopamine D2 receptor antagonist, used for the treatment of nausea and vomiting.

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Biological Activity

Description Metoclopramide HCl is a selective dopamine D2 receptor antagonist, used for the treatment of nausea and vomiting.
Targets
D2 receptor [1]

Protocol

References

Solubility (25°C)

In vitro DMSO 67 mg/mL warmed (199.25 mM)
Water 67 mg/mL (199.25 mM)
Ethanol 67 mg/mL (199.25 mM)
In vivo

* 1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 336.26
Formula

C14H23Cl2N3O2

CAS No. 7232-21-5
Storage powder
in solvent
Synonyms N/A

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Clinical Trial Information

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT02582996 Not yet recruiting Migraine Ache Laboratorios Farmaceuticos S.A. April 2018 Phase 3
NCT02907632 Not yet recruiting Gastroesophageal Reflux Nathalie Charpak|Hospital Universitario San Ignacio|Pontificia Universidad Javeriana|Kangaroo Foundation January 2017 Phase 4
NCT03017391 Not yet recruiting Nausea|Vomiting|Cancer Radboud University January 2017 Phase 4
NCT03023306 Not yet recruiting Postoperative Nausea and Vomiting University of Athens January 2017 --
NCT02979548 Recruiting Chemotherapy Induced Vomiting|Acute Myeloid Leukemia Dr Atul Sharma|All India Institute of Medical Sciences, New Delhi November 2016 Phase 3
NCT02965963 Not yet recruiting Health University of Alberta|Natural Sciences and Engineering Research Council, Canada November 2016 --

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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Dopamine Receptor Signaling Pathway Map

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID