Metoclopramide HCl

Synonyms: Metoclopramide hydrochloride

Metoclopramide HCl(Metoclopramide hydrochloride) is a selective dopamine D2 receptor antagonist, used for the treatment of nausea and vomiting.

Metoclopramide HCl Chemical Structure

Metoclopramide HCl Chemical Structure

CAS: 7232-21-5

Selleck's Metoclopramide HCl has been cited by 3 publications

Purity & Quality Control

Batch: S428901 DMSO] 67 mg/mL] false] Water] 67 mg/mL] false] Ethanol] 67 mg/mL] false Purity: 99.72%
99.72

Metoclopramide HCl Related Products

Choose Selective Dopamine Receptor Inhibitors

Biological Activity

Description Metoclopramide HCl(Metoclopramide hydrochloride) is a selective dopamine D2 receptor antagonist, used for the treatment of nausea and vomiting.
Targets
D2 receptor [1]
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT05759481 Not yet recruiting
Post-operative Nausea and Vomiting
Milton S. Hershey Medical Center
January 2024 Phase 2
NCT05832151 Recruiting
Diabetic Gastroparesis
CinDome Pharma Inc.
March 27 2023 Phase 2
NCT05008926 Recruiting
Brain Injuries
University Hospital Brest
March 15 2022 Phase 3
NCT04748133 Unknown status
Treatment Complication
Zagazig University
February 20 2021 Not Applicable
NCT02466984 Completed
Nausea|Vomiting
University Hospital Bordeaux
July 2016 Phase 3

Chemical Information & Solubility

Molecular Weight 336.26 Formula

C14H23Cl2N3O2

CAS No. 7232-21-5 SDF Download Metoclopramide HCl SDF
Smiles CCN(CC)CCNC(=O)C1=CC(=C(C=C1OC)N)Cl.Cl
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 67 mg/mL ( (199.25 mM); Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : 67 mg/mL

Ethanol : 67 mg/mL


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In vivo
Batch:

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In vivo Formulation Calculator

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In vivo Formulation Calculator (Clear solution)

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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