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United States ( Change Country )
Metformin hydrochloride(Glucophage) Chemical Structure
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Biological Activity
Metformin hydrochloride(Glucophage) is a biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. Metformin’s pharmacologic mechanisms of action are different from other classes of oral antihyperglycemic agents. Metformin decreases hepatic glucose production, decreases intestinal absorption of glucose, and improves insulin sensitivity by increasing peripheral glucose uptake and utilization. [1]
Chemical Information
| Molecular Weight (WM): | 165.62 |
|---|---|
| Formula: | C4H11N5.HCl |
| CAS No.: | 1115-70-4 |
| Synonyms: |
Glucophage, Riomet, Diabex
|
| Dissolve in (25°C): | DMSO ≥16mg/mL |
| Water ≥33mg/mL | |
| Ethanol <1mg/mL | |
| Storage: | 2 years-20°CPowder |
| 1 week-4°Cin DMSO | |
| 1 month-80°in DMSO |
Quality Control & MSDS
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