Histone Acetyltransferase

Sigaling Pathway Map

Research Area

  • Inhibitory Selectivity
  • Solubility
Catalog No. Product Name Solubility(25°C)
Water DMSO Alcohol
S7152 C646 <1 mg/mL 13 mg/mL <1 mg/mL
S1848 Curcumin <1 mg/mL 74 mg/mL <1 mg/mL
S7582 Anacardic Acid <1 mg/mL 69 mg/mL 69 mg/mL
S7641 Remodelin <1 mg/mL 72 mg/mL <1 mg/mL
S7476 MG149 <1 mg/mL 68 mg/mL 68 mg/mL
Catalog No. Information Product Use Citations Product Validations
S7152

C646

C646 is an inhibitor for histone acetyltransferase, and inhibits p300 with a Ki of 400 nM in a cell-free assay. Preferentially selective for p300 versus other acetyltransferases.

S1848

Curcumin

Curcumin is the principal curcuminoid of the popular Indian spice turmeric, which is a member of the ginger family (Zingiberaceae). It is an inhibitor of p300 histone acetylatransferase(IC50~25 μM) and Histone deacetylase; activates Nrf2 pathway and supresses the activation of transcription factor NF-κB.

S7582

Anacardic Acid

Anacardic Acid is a potent inhibitor of p300 and p300/CBP-associated factor histone acetyltranferases, which also has antibacterial activity, antimicrobial activity, prostaglandin synthase inhibition, and tyrosinase and lipoxygenase inhibition.

S7641

Remodelin

Remodelin is a potent acetyl-transferase NAT10 inhibitor.

S7476

MG149

MG149 is a potent histone acetyltransferase inhibitor with IC50 of 74 μM and 47 μM for Tip60 and MOF,respectively.

Catalog No. Information Product Use Citations Product Validations
S7152

C646

C646 is an inhibitor for histone acetyltransferase, and inhibits p300 with a Ki of 400 nM in a cell-free assay. Preferentially selective for p300 versus other acetyltransferases.

S1848

Curcumin

Curcumin is the principal curcuminoid of the popular Indian spice turmeric, which is a member of the ginger family (Zingiberaceae). It is an inhibitor of p300 histone acetylatransferase(IC50~25 μM) and Histone deacetylase; activates Nrf2 pathway and supresses the activation of transcription factor NF-κB.

S7582

Anacardic Acid

Anacardic Acid is a potent inhibitor of p300 and p300/CBP-associated factor histone acetyltranferases, which also has antibacterial activity, antimicrobial activity, prostaglandin synthase inhibition, and tyrosinase and lipoxygenase inhibition.

S7641

Remodelin

Remodelin is a potent acetyl-transferase NAT10 inhibitor.

S7476

MG149

MG149 is a potent histone acetyltransferase inhibitor with IC50 of 74 μM and 47 μM for Tip60 and MOF,respectively.