Opioid Receptor

  • Compare Opioid Receptor Products
  • Research Area

Opioid Receptor Agonists | Antagonists (10)

water-soluble

Cat.No. Product Name Information Product Use Citation Customer Product Validation
S2480 Loperamide HCl Loperamide HCl is a selective μ-opioid receptor agonist opioid with Ki of 3.3 nM, 15-fold and 350-fold selective over the δ subtype and the κ subtype of the opioid receptor, used against diarrhea resulting from gastroenteritis or inflammatory bowel disease.
  • Antimicrob Agents Chemother, 2014, 58(8):4875-84
S3066 Naloxone HCl Naloxone HCl is an opioid inverse agonist drug used to counter the effects of opiate overdose.
S2722 JTC-801 JTC-801 is a selective opioid receptor-like1 (ORL1) receptor antagonist with IC50 of 94 nM, weakly inhibits receptors δ, κ, and μ.
S1139 ADL5859 HCl ADL5859 HCl is a δ-opioid receptor agonist with Ki of 0.8 nM, selectivity against opioid receptor κ, μ, and weak inhibitory activity at the hERG channel. Phase 2.
  • Expert Opin Inv Drugs, 2012, 21(11):1607-18
S2103 Naltrexone HCl Naltrexone HCl is an opioid receptor antagonist used primarily in the management of alcohol dependence and opioid dependence.
  • Sci Rep, 2014, 4:7270
S4501 Naloxone HCl Dihydrate Naloxone HCl Dihydrate is an opioid inverse agonist drug used to counter the effects of opiate overdose.
S2503 Racecadotril Racecadotril is a peripherally acting enkephalinase inhibitor with an IC50 of 4.5 μM.
S2322 (+)-Matrine Matrine((+)-Matrine) is an alkaloid found in plants from the Sophora family, which has a variety of pharmacological effects, including anti-cancer effects, and action as a kappa opioid receptor agonist.
S3204 Meptazinol HCl Meptazinol is a unique centrally active opioid analgesic, which inhibits [3H]dihydromorphine binding with IC50 of 58 nM.
S2085 Trimebutine Trimebutine is an agonist of peripheral mu, kappa and delta opiate receptors, used as spasmolytic agent for treatment of both acute and chronic abdominal pain.

Hover Mouse over '+' to display IC50

Cat.No. Product Name Solubility (25°C)
Water DMSO Ethanol
S2480 Loperamide HCl <1 mg/mL 22 mg/mL 4 mg/mL
S3066 Naloxone HCl 73 mg/mL 73 mg/mL <1 mg/mL
S2722 JTC-801 <1 mg/mL 90 mg/mL 31 mg/mL
S1139 ADL5859 HCl 5 mg/mL 86 mg/mL 1 mg/mL
S2103 Naltrexone HCl 14 mg/mL 14 mg/mL <1 mg/mL
S4501 Naloxone HCl Dihydrate 20 mg/mL 79 mg/mL <1 mg/mL
S2503 Racecadotril <1 mg/mL 22 mg/mL 77 mg/mL
S2322 (+)-Matrine 11 mg/mL 49 mg/mL 49 mg/mL
S3204 Meptazinol HCl 54 mg/mL 54 mg/mL 54 mg/mL
S2085 Trimebutine <1 mg/mL 50 mg/mL <1 mg/mL
Contact Us