Selective Inhibitors | Agonists | Antagonists

Catalog No. Product Name Information Selective / Pan IC50 / Ki
S2103 Naltrexone HCl

Naltrexone HCl is an opioid receptor antagonist with IC50 of 8 nM used primarily in the management of alcohol dependence and opioid dependence.

Selective opioid receptor, IC50: 8 nM
S3204 Meptazinol HCl

Meptazinol is a unique centrally active opioid analgesic, which inhibits [3H]dihydromorphine binding with IC50 of 58 nM.

Selective
S2503 Racecadotril

Racecadotril is a peripherally acting enkephalinase inhibitor with an IC50 of 4.5 μM

Selective
S3066 Naloxone HCl

Naloxone HCl is an opioid inverse agonist drug used to counter the effects of opiate overdose.

Selective
S2480 Loperamide HCl

Loperamide HCl is an opioid-receptor agonist with an ED50 of 0.15 mg/kg.

Selective
S1139 ADL5859 HCl

ADL5859 HCl is a δ-opioid receptor agonist with Ki of 0.8 nM, selectivity against opioid receptor κ, μ, and weak inhibitory activity at the hERG channel. Phase 2.

Pan μ-opioid receptor, Ki: 32 nM