κ-opioid receptor Selective Agonists

Catalog No. Product Name Information Selective / Pan IC50 / Ki
S2322 (+)-Matrine

Matrine((+)-Matrine) is an alkaloid found in plants from the Sophora family, which has a variety of pharmacological effects, including anti-cancer effects, and action as a kappa opioid receptor agonist.

Selective
S1139 ADL5859 HCl

ADL5859 HCl is a δ-opioid receptor agonist with Ki of 0.8 nM, selectivity against opioid receptor κ, μ, and weak inhibitory activity at the hERG channel. Phase 2.

Pan κ-opioid receptor, Ki: 37 nM