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S2005
|
Raltegravir (MK-0518) |
Raltegravir (MK-0518, Isentress) is a potent integrase (IN) inhibitor for WT and S217Q PFV IN with IC50 of 90 nM and 40 nM, respectivly. |
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S2001
|
Elvitegravir (GS-9137) |
Elvitegravir (EVG, JTK-303/GS-9137) is a HIV integrase inhibitor for HIV-1 IIIB, HIV-2 EHO and HIV-2 ROD with IC50 of 0.7 nM, 2.8 nM and 1.4 nM, respectively. |
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S1366
|
BMS-707035 |
BMS-707035 is a specific HIV-I integrase (IN) inhibitor with IC50 of 15 nM. |
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S2765
|
MK-2048 |
MK-2048 is an potent inhibitor of integrase (IN) and INR263K with IC50 of 2.6 nM and 1.5 nM, respectively. |
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S2667
|
S/GSK1349572 (GSK1349572) |
S/GSK1349572 (GSK1349572) is a two-metal-binding HIV integrase inhibitor with IC50 of 2.7 nM. |
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