ribosome

Microbiology

DPP Aminopeptidase Procollagen C Proteinase P450 (e.g. CYP17) Phospholipase (e.g. PLA) Factor Xa PDE DHFR Carbonic Anhydrase Hydroxylase Liver X Receptor FAAH Acyltransferase Dehydrogenase Phosphorylase PPAR CYP17 FXR HMG-CoA Reductase Transferase IDO/TDO Retinoid Receptor Casein Kinase NAMPT phosphatase Lipase Lipoxygenase Thioredoxin Decarboxylase Vitamin Serine/threonin kinase LDL Fatty Acid Synthase FOX Glycogen synthesis PKM Glycolysis HDL Carbohydrate Metabolism ATP-citrate lyase Acetyl-CoA carboxylase CYP450 PCSK9 Leukotriene PDHK PGC-1α ROR FABP Peroxidases Aldose Reductase Xanthine Oxidase THR Epoxide Hydrolase PEP GTPCH FAO PAI-1 LDH SCD PREP CPSase Mannosidase Thioredoxin Reductase SGK FTase γGCS CPT SREBP Mitochondrial Metabolism PARG Glucosylceramide Synthase Catalase 3-MST Serine hydrolase CAR glucocerebrosidase Mitochondrial pyruvate carrier GOT SHIP SOD LCN Endogenous Metabolite ATGL NMT Aconitase AGEs Amino Acids and Derivatives Amylase Drug Metabolite Glucokinase Glucosidase glycosidase GSNOR GST Hexokinase Isocitrate Dehydrogenase (IDH) Lipid Liposome LPL Receptor MAGL NEDD4-1 NPC1L1 PGK1 Reductase stilbene oxidase UGT

All (22)
ribosome Inhibitors (17)
New ribosome Products

Cat.No.	Product Name	Information	Product Use Citations
S1773	Oxytetracycline (Terramycin)	Oxytetracycline (Terramycin) is a broad-spectrum tetracycline antibiotic used to treat infections with bacteria.	Sci Rep, 2018, 8(1):7653 Front Microbiol, 2016, 7: 1765
E4932	Amikacin	Amikacin(BAY 41-6551, Lukadin) is a semisynthetic aminoglycoside, derived from kanamycin-A, that acts as an inhibitor of the Z ring formation, leading to the inhibition of cell division. It is used to treat serious infections caused by aerobic Gram-negative bacteria, mycobacteria, Nocardia, and life-threatening infections in neonates.
S7417	Puromycin Dihydrochloride	Puromycin 2HCl is an aminonucleoside antibiotic derived from Streptomyces alboniger. It is an inhibitor of protein synthesis and has been used to study transcription regulatory mechanisms that control the sequential and coordinated expression of genes during cell differentiation.	Signal Transduct Target Ther, 2025, 10(1):182 Cell Stem Cell, 2025, S1934-5909(25)00181-X Nat Commun, 2025, 16(1):4792
S4163	Doxycycline Hyclate	Doxycycline Hyclate is a member of the tetracycline antibiotics group, and is commonly used to treat a variety of infections. It is also an inhibitor of matrix metallo-proteinases (MMP).	Cell Discov, 2025, 11(1):41 Adv Sci (Weinh), 2025, 12(41):e03977 Dev Cell, 2025, S1534-5807(25)00405-8
S5159	Doxycycline	Doxycycline (Vibramycin, Doxytetracycline, Doxiciclina, Doxycyclinum) is an antibiotic that is used in the treatment of a number of types of infections caused by bacteria and protozoa. Doxycycline is also a nonspecific matrix metalloproteinase (MMP) inhibitor.	Nature, 2025, 10.1038/s41586-025-09222-5 Cell Stem Cell, 2025, S1934-5909(25)00181-X Nat Commun, 2025, 16(1):7898
S1403	Tigecycline	Tigecycline is bacteriostatic and is a protein synthesis inhibitor by binding to the 30S ribosomal subunit of bacteria and thereby blocking entry of Aminoacyl-tRNA into the A site of the ribosome during prokaryotic translation. This compound induces autophagy by downregulating the PI3K-AKT-mTOR pathway.	J Infect Dis, 2025, 232(3):e416-e420 NPJ Antimicrob Resist, 2025, 3(1):12 Int J Mol Sci, 2024, 25(9)4887
S2572	Streptomycin sulfate	Streptomycin sulfate(Phytomycin) is a sulfate salt of streptomycin that is a protein synthesis inhibitor.	Front. Oncol, 2023-, Volume 13 Front Oncol, 2023, 13:1118268 Transl Oncol, 2022, 26:101502
S2908	Hygromycin B	Hygromycin B (Hygrovetine), a selective antibiotic that is effective on most bacteria, fungi and higher eukaryotes, inhibits protein synthesis by interfering with translocation and causing mistranslation at the 70S ribosome.	Nat Commun, 2024, 15(1):10594 Redox Biol, 2024, 76:103349 Front Pharmacol, 2024, 15:1432851
S4147	Azithromycin Dihydrate	Azithromycin Dihydrate(CP-62993 dihydrate) is an acid stable orally administered macrolide antimicrobial drug, structurally related to erythromycin.	J Cell Biochem, 2022, 10.1002/jcb.30213 Adv Ther (Weinh), 2020, 2000034 PLoS Comput Biol, 2020, 16(12):e1008489
S2555	Clarithromycin	Clarithromycin (A-56268) is a macrolide antibiotic and a CYP3A4 inhibitor, used to treat a number of bacterial infections.	Circulation, 2024, 150(7):563-576 Microorganisms, 2022, 10(7)1421 Cell Biol Toxicol, 2021, 10.1007/s10565-021-09646-5
S1635	Erythromycin	Erythromycin (E-Mycin) is a macrolide antibiotic that has an antimicrobial spectrum similar to or slightly wider than that of penicillin (IC50=1.5 μg/ml).	Autophagy, 2025, 1-17. Infect Drug Resist, 2023, 16:4867-4879 Infect Drug Resist, 2023, 16:4867-4879
S2574	Tetracycline HCl	Tetracycline HCl (NCI-c55561) is a hydrochloride salt of tetracycline that is a broad-spectrum polyketide antibiotic.	Nat Commun, 2024, 15(1):2377 Antiviral Res, 2020, 185:104993 PLoS Pathog, 2020, 16;16(3):e1008341
S4056	Retapamulin	Retapamulin (SB-275833) is a topical antibiotic, which binds to both E. coli and S. aureus ribosomes with similar potencies with K_d of 3 nM.	Infect Drug Resist, 2023, 16:4867-4879 Infect Drug Resist, 2023, 16:4867-4879 Pediatr Infect Dis J, 2021, 40(7):637-638
S1677	Chloramphenicol	Chloramphenicol (Chloromycetin) is a bacteriostatic by inhibiting protein synthesis.	Cell Rep, 2021, 34(3):108631 EMBO Rep, 2021, e53081 Oncotarget, 2018, 9(40):26086-26095
S4279	Demeclocycline HCl	Demeclocycline HCl(Demeclocycline hydrochloride) is a tetracycline antibiotic via inhibition of protein synthesis by bacteria, used for the treatment of bacterial infections.	Cancer Res Commun, 2025, 10.1158/2767-9764.CRC-24-0433 J Biol Chem, 2020, 10.1074/jbc.RA119.011633. Sci Rep, 2018, 8(1):7653
S2510	Spectinomycin 2HCl	Spectinomycin 2HCl (Actinospectacin) is a new parenteral antibiotic prepared from Streptomyces spectabilis.	Cell Rep, 2020, 32(2):107897
S2514	Tobramycin	Tobramycin (NSC 180514,Deoxykanamycin B, Nebramycin Factor 6) is an aminoglycoside antibiotic with an IC50 of 9.7 μM.	Oncotarget, 2018, 9(40):26086-26095
S4490	Tetracycline	Tetracycline (TC) is a broad-spectrum antibiotic that exhibits activity against a wide range of microorganisms including gram-positive and gram-negative bacteria, chlamydiae, mycoplasmas, rickettsiae, and protozoan parasites.	Redox Biol, 2025, 84:103649 bioRxiv, 2025, 2025.01.08.632009 PeerJ, 2022, 10:e13719
S3496	Lefamulin acetate (Xenleta)	Lefamulin acetate (Xenleta, BC-3781 acetate) is a pleuromutilin antibiotic for community-acquired bacterial pneumonia (CABP) treatment. It inhibits protein synthesis by binding to the peptidyl transferase center of the 50S bacterial ribosome, thus preventing the binding of transfer RNA for peptide transfer.	J Biol Chem, 2022, 298(5):101909
S2315	Kanamycin sulfate	Kanamycin sulfate (Kanamycin monosulfate, Ophtalmokalixan) is an aminoglycoside antibiotic, available in oral, intravenous, and intramuscular forms, and used to treat a wide variety of infections.	Heliyon, 2024, 10(11):e32571 Oncotarget, 2018, 9(40):26086-26095
S5417	Spectinomycin dihydrochloride pentahydrate	Spectinomycin dihydrochloride pentahydrate (Trobicin) is a widely used antibiotic that inhibits bacterial protein synthesis by blocking translocation of messenger RNA and transfer RNAs on the ribosome.
E4867	Omadacycline	Omadacycline(Amadacycline) is an oral aminomethylcycline antibacterial antibiotic used to treat moderate-to-severe infections, such as community-acquired pneumonia and acute bacterial skin and skin structure infections caused by susceptible organisms. It inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit. This compound has broad-spectrum antibacterial activity and is effective against Gram-positive and Gram-negative aerobic, anaerobic, and atypical bacteria.
S1773	Oxytetracycline (Terramycin)	Oxytetracycline (Terramycin) is a broad-spectrum tetracycline antibiotic used to treat infections with bacteria.	Sci Rep, 2018, 8(1):7653 Front Microbiol, 2016, 7: 1765
S7417	Puromycin Dihydrochloride	Puromycin 2HCl is an aminonucleoside antibiotic derived from Streptomyces alboniger. It is an inhibitor of protein synthesis and has been used to study transcription regulatory mechanisms that control the sequential and coordinated expression of genes during cell differentiation.	Signal Transduct Target Ther, 2025, 10(1):182 Cell Stem Cell, 2025, S1934-5909(25)00181-X Nat Commun, 2025, 16(1):4792
S4163	Doxycycline Hyclate	Doxycycline Hyclate is a member of the tetracycline antibiotics group, and is commonly used to treat a variety of infections. It is also an inhibitor of matrix metallo-proteinases (MMP).	Cell Discov, 2025, 11(1):41 Adv Sci (Weinh), 2025, 12(41):e03977 Dev Cell, 2025, S1534-5807(25)00405-8
S5159	Doxycycline	Doxycycline (Vibramycin, Doxytetracycline, Doxiciclina, Doxycyclinum) is an antibiotic that is used in the treatment of a number of types of infections caused by bacteria and protozoa. Doxycycline is also a nonspecific matrix metalloproteinase (MMP) inhibitor.	Nature, 2025, 10.1038/s41586-025-09222-5 Cell Stem Cell, 2025, S1934-5909(25)00181-X Nat Commun, 2025, 16(1):7898
S1403	Tigecycline	Tigecycline is bacteriostatic and is a protein synthesis inhibitor by binding to the 30S ribosomal subunit of bacteria and thereby blocking entry of Aminoacyl-tRNA into the A site of the ribosome during prokaryotic translation. This compound induces autophagy by downregulating the PI3K-AKT-mTOR pathway.	J Infect Dis, 2025, 232(3):e416-e420 NPJ Antimicrob Resist, 2025, 3(1):12 Int J Mol Sci, 2024, 25(9)4887
S2572	Streptomycin sulfate	Streptomycin sulfate(Phytomycin) is a sulfate salt of streptomycin that is a protein synthesis inhibitor.	Front. Oncol, 2023-, Volume 13 Front Oncol, 2023, 13:1118268 Transl Oncol, 2022, 26:101502
S2908	Hygromycin B	Hygromycin B (Hygrovetine), a selective antibiotic that is effective on most bacteria, fungi and higher eukaryotes, inhibits protein synthesis by interfering with translocation and causing mistranslation at the 70S ribosome.	Nat Commun, 2024, 15(1):10594 Redox Biol, 2024, 76:103349 Front Pharmacol, 2024, 15:1432851
S2555	Clarithromycin	Clarithromycin (A-56268) is a macrolide antibiotic and a CYP3A4 inhibitor, used to treat a number of bacterial infections.	Circulation, 2024, 150(7):563-576 Microorganisms, 2022, 10(7)1421 Cell Biol Toxicol, 2021, 10.1007/s10565-021-09646-5
S1635	Erythromycin	Erythromycin (E-Mycin) is a macrolide antibiotic that has an antimicrobial spectrum similar to or slightly wider than that of penicillin (IC50=1.5 μg/ml).	Autophagy, 2025, 1-17. Infect Drug Resist, 2023, 16:4867-4879 Infect Drug Resist, 2023, 16:4867-4879
S2574	Tetracycline HCl	Tetracycline HCl (NCI-c55561) is a hydrochloride salt of tetracycline that is a broad-spectrum polyketide antibiotic.	Nat Commun, 2024, 15(1):2377 Antiviral Res, 2020, 185:104993 PLoS Pathog, 2020, 16;16(3):e1008341
S1677	Chloramphenicol	Chloramphenicol (Chloromycetin) is a bacteriostatic by inhibiting protein synthesis.	Cell Rep, 2021, 34(3):108631 EMBO Rep, 2021, e53081 Oncotarget, 2018, 9(40):26086-26095
S2510	Spectinomycin 2HCl	Spectinomycin 2HCl (Actinospectacin) is a new parenteral antibiotic prepared from Streptomyces spectabilis.	Cell Rep, 2020, 32(2):107897
S2514	Tobramycin	Tobramycin (NSC 180514,Deoxykanamycin B, Nebramycin Factor 6) is an aminoglycoside antibiotic with an IC50 of 9.7 μM.	Oncotarget, 2018, 9(40):26086-26095
S4490	Tetracycline	Tetracycline (TC) is a broad-spectrum antibiotic that exhibits activity against a wide range of microorganisms including gram-positive and gram-negative bacteria, chlamydiae, mycoplasmas, rickettsiae, and protozoan parasites.	Redox Biol, 2025, 84:103649 bioRxiv, 2025, 2025.01.08.632009 PeerJ, 2022, 10:e13719
S3496	Lefamulin acetate (Xenleta)	Lefamulin acetate (Xenleta, BC-3781 acetate) is a pleuromutilin antibiotic for community-acquired bacterial pneumonia (CABP) treatment. It inhibits protein synthesis by binding to the peptidyl transferase center of the 50S bacterial ribosome, thus preventing the binding of transfer RNA for peptide transfer.	J Biol Chem, 2022, 298(5):101909
S2315	Kanamycin sulfate	Kanamycin sulfate (Kanamycin monosulfate, Ophtalmokalixan) is an aminoglycoside antibiotic, available in oral, intravenous, and intramuscular forms, and used to treat a wide variety of infections.	Heliyon, 2024, 10(11):e32571 Oncotarget, 2018, 9(40):26086-26095
E4867	Omadacycline	Omadacycline(Amadacycline) is an oral aminomethylcycline antibacterial antibiotic used to treat moderate-to-severe infections, such as community-acquired pneumonia and acute bacterial skin and skin structure infections caused by susceptible organisms. It inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit. This compound has broad-spectrum antibacterial activity and is effective against Gram-positive and Gram-negative aerobic, anaerobic, and atypical bacteria.