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3C-Like Protease

Other Microbiology Related Inhibitors

Integrase Reverse Transcriptase Anti-infection Ribosomal Peptidyl Transferase COVID-19 β-lactamase Parasite Neuraminidase CMV Fungal
Cat.No. Product Name Information Product Use Citations Product Validations
S0475 GC376 GC376 is a 3CLpro (3C-like protease) inhibitor with IC50 of ~ 1.11 μM for the PEDV 3CLpro. This compound is active against the 3CLpro of multiple coronaviruses, including SARS-CoV.
PLoS Pathog, 2025, 21(8):e1013401
Commun Biol, 2025, 8(1):1061
J Virol, 2025, 99(6):e0035425
S6872 Merbromin Merbromin (Mercurochrome), a xanthene dye and an antibacterial agent, is the first of a series of antiseptics that contained mercury, also is a mixed-type inhibitor of 3CLpro due to its ability of increasing the KM and decreasing the Kcat of 3CLpro.
S9018 Luteoloside Luteoloside (Cynaroside, Luteolin 7-β-D-Glucopyranoside) is a member of the flavonoids family that exhibits several bioactivities including anti-microbial and anti-cancer activities. It is an inhibitor of 3C Protease of Enterovirus 71 with an IC50 value of 0.36 mM.
Histol Histopathol, 2025, 18922
Pharmaceuticals (Basel), 2023, 16(4)548