3C-Like Protease antagonist | 3C-Like Protease inhibitor | 3C-Like Protease agonist

Catalog No.	Product Name	Information	Product Use Citations
S0475	GC376	GC376 is a 3CLpro (3C-like protease) inhibitor with IC50 of ~ 1.11 μM for the PEDV 3CLpro. GC376 is active against the 3CLpro of multiple coronaviruses, including SARS-CoV.	Int J Mol Sci, 2024, 25(11)5767 J Virol, 2024, 98(7):e0052324 J Virol, 2024, 98(2):e0199423
S9018	Luteoloside	Luteoloside (Cynaroside, Luteolin 7-β-D-Glucopyranoside) is a member of the flavonoids family that exhibits several bioactivities including anti-microbial and anti-cancer activities. It is an inhibitor of 3C Protease of Enterovirus 71 with an IC50 value of 0.36 mM.	Histol Histopathol, 2025, 18922 Pharmaceuticals (Basel), 2023, 16(4)548
S6872	Merbromin	Merbromin (Mercurochrome), a xanthene dye and an antibacterial agent, is the first of a series of antiseptics that contained mercury, also is a mixed-type inhibitor of 3CLpro due to its ability of increasing the K_M and decreasing the K_cat of 3CLpro.
S0475	GC376	GC376 is a 3CLpro (3C-like protease) inhibitor with IC50 of ~ 1.11 μM for the PEDV 3CLpro. GC376 is active against the 3CLpro of multiple coronaviruses, including SARS-CoV.	Int J Mol Sci, 2024, 25(11)5767 J Virol, 2024, 98(7):e0052324 J Virol, 2024, 98(2):e0199423
S9018	Luteoloside	Luteoloside (Cynaroside, Luteolin 7-β-D-Glucopyranoside) is a member of the flavonoids family that exhibits several bioactivities including anti-microbial and anti-cancer activities. It is an inhibitor of 3C Protease of Enterovirus 71 with an IC50 value of 0.36 mM.	Histol Histopathol, 2025, 18922 Pharmaceuticals (Basel), 2023, 16(4)548
S6872	Merbromin	Merbromin (Mercurochrome), a xanthene dye and an antibacterial agent, is the first of a series of antiseptics that contained mercury, also is a mixed-type inhibitor of 3CLpro due to its ability of increasing the K_M and decreasing the K_cat of 3CLpro.

3C-Like Protease

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