| E4932 |
Amikacin
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Amikacin(BAY 41-6551, Lukadin) is a semisynthetic aminoglycoside, derived from kanamycin-A, that acts as an inhibitor of the Z ring formation, leading to the inhibition of cell division. It is used to treat serious infections caused by aerobic Gram-negative bacteria, mycobacteria, Nocardia, and life-threatening infections in neonates.
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| S4147 |
Azithromycin Dihydrate
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Azithromycin Dihydrate(CP-62993 dihydrate) is an acid stable orally administered macrolide antimicrobial drug, structurally related to erythromycin.
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J Cell Biochem, 2022, 10.1002/jcb.30213
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Adv Ther (Weinh), 2020, 2000034
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PLoS Comput Biol, 2020, 16(12):e1008489
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| S4056 |
Retapamulin
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Retapamulin (SB-275833) is a topical antibiotic, which binds to both E. coli and S. aureus ribosomes with similar potencies with Kd of 3 nM.
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Infect Drug Resist, 2023, 16:4867-4879
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Pediatr Infect Dis J, 2021, 40(7):637-638
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Hum Mol Genet, 2020, ddaa244
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| S4279 |
Demeclocycline HCl
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Demeclocycline HCl(Demeclocycline hydrochloride) is a tetracycline antibiotic via inhibition of protein synthesis by bacteria, used for the treatment of bacterial infections.
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Cancer Res Commun, 2025, 10.1158/2767-9764.CRC-24-0433
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J Biol Chem, 2020, 10.1074/jbc.RA119.011633.
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Sci Rep, 2018, 8(1):7653
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| S5417 |
Spectinomycin dihydrochloride pentahydrate
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Spectinomycin dihydrochloride pentahydrate (Trobicin) is a widely used antibiotic that inhibits bacterial protein synthesis by blocking translocation of messenger RNA and transfer RNAs on the ribosome.
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