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Guanidinoacetic acid

Cat.No.S6340

Guanidinoacetic acid (Guanidino acetic acid, GAA, Glycocyamine, Guanidinoacetate), the natural precursor of creatine, is under investigation as a dietary agent. This compound exhibits potential ergogenic benefits for physically active men and women.
Guanidinoacetic acid Chemical Structure

Chemical Structure

Molecular Weight: 117.11

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Quality Control

Batch: S634001 4-Methylpyridine]5 mg/mL]true]DMSO]Insoluble]false]Water]Insoluble]false Purity: 98.5%
98.5

Solubility

In vitro
Batch:

4-Methylpyridine : 5 mg/mL

DMSO : Insoluble
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)

Water : Insoluble

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In vivo
Batch:

In vivo Formulation Calculator (Clear solution)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Chemical Information, Storage & Stability

Molecular Weight 117.11 Formula

C3H7N3O2

 Storage (From the date of receipt) 3 years -20°C powder
CAS No. 352-97-6 -- Storage of Stock Solutions

Mechanism of Action

References

Clinical Trial Information

(data from https://clinicaltrials.gov, updated on 2024-05-22)

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT06391736 Recruiting
Pompe Disease (Late-onset)
GeneCradle Inc
 April 19 2024 Phase 1|Phase 2
NCT06150820 Recruiting
Pompe Disease (Late-onset)
Astellas Gene Therapies|Astellas Pharma Inc
 February 1 2024 Not Applicable
NCT05312736 Recruiting
Gyrate Atrophy|Gyrata of Choroid and Retina; Atrophy|Ornithine-δ-aminotransferase|OAT|Chorioretinal Degeneration
Jaeb Center for Health Research|Conquering Gyrate Atrophy Foundation|Food and Drug Administration (FDA)|Department of Health and Human Services
 November 21 2023 --
NCT05874388 Not yet recruiting
Friedreich Ataxia
Institut National de la Santé Et de la Recherche Médicale France
 September 1 2023 Not Applicable
NCT05448131 Recruiting
Pompe-Disease
Centre for Analytical Biochemistry and Biomedical Mass Spectrometry|University of Giessen
 February 1 2023 --

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