PTP Inhibitor II

Catalog No.S3678 Synonyms: NSC 129010, 4-(Bromoacetyl)anisole

PTP Inhibitor II Chemical Structure

Molecular Weight(MW): 229.07

PTP Inhibitor II is a cell-permeable protein tyrosine phosphatase (PTP) inhibitor that covalently binds the catalytic domain of the Src homology region 2 domain-containing phosphatase (SHP-1(ΔSH2)) with Ki value of 128 μM.

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Biological Activity

Description PTP Inhibitor II is a cell-permeable protein tyrosine phosphatase (PTP) inhibitor that covalently binds the catalytic domain of the Src homology region 2 domain-containing phosphatase (SHP-1(ΔSH2)) with Ki value of 128 μM.
Targets
SHP-1(ΔSH2) [1]
(Cell-free)
128 μM(Ki)

Protocol

Solubility (25°C)

In vitro DMSO 45 mg/mL (196.44 mM)
Ethanol 45 mg/mL (196.44 mM)
Water Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 229.07
Formula

C9H9BrO2

CAS No. 2632-13-5
Storage powder
in solvent
Synonyms NSC 129010, 4-(Bromoacetyl)anisole

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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID