CAS No. 2632-13-5
Batch:
Purity:99.56
Chemical Structure
Check the
PTP Inhibitor II
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | 2-bromo-1-(4-methoxyphenyl)ethanone | |
|---|---|---|
| CAS Number | 2632-13-5 | |
| Molecular Formula |
C9H9BrO2 |
|
| Molecular Weight (MW) | 229.07 | |
| SMILES | COC1=CC=C(C=C1)C(=O)CBr | |
| InChIKey | XQJAHBHCLXUGEP-UHFFFAOYSA-N |
PTP Inhibitor II is a cell-permeable protein tyrosine phosphatase (PTP) inhibitor that covalently binds to the catalytic domain of Src homology region 2 domain-containing phosphatase 1 (SHP-1). By inhibiting SHP-1-mediated protein dephosphorylation, this agent alters key tyrosine phosphorylation pathways, thereby influencing downstream cellular signal transduction, immune receptor signaling, and cell growth processes. [1][2]
|
Concentration
Volume
Mass
|
1 mg | 5 mg | 10 mg |
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
45 mg/mL
(196.44 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 45 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.