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Catalog No.S1996 Synonyms: GR 38032F, GR-C507/75

1 publication

Ondansetron Chemical Structure

CAS No. 99614-02-5

Ondansetron (GR 38032F, GR-C507/75) is a serotonin 5-HT3 receptor antagonist used mainly as an antiemetic.

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Selleck's Ondansetron has been cited by 1 publication

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  • Mean (±SEM) cumulative 5-HT concentration–response curves in the absence and presence of 5-HT antagonists (n = >8). Responses are expressed as a percentage of the maximum response for each curve.

    Int J Urol, 2016, 23(11):946-951. Ondansetron purchased from Selleck.

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Biological Activity

Description Ondansetron (GR 38032F, GR-C507/75) is a serotonin 5-HT3 receptor antagonist used mainly as an antiemetic.
5-HT3 [1]



Solubility (25°C)

In vitro DMSO 0.1 mg/mL (0.34 mM)
Water Insoluble
Ethanol Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 293.36


CAS No. 99614-02-5
Storage powder
in solvent
Synonyms GR 38032F, GR-C507/75
Smiles CC1=NC=CN1CC2CCC3=C(C2=O)C4=CC=CC=C4N3C

In vivo Formulation Calculator (Clear solution)

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Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT04226170 Not yet recruiting Drug: DAS-001 Myasthenia Gravis DAS-MG Inc September 30 2020 Phase 2
NCT04167813 Not yet recruiting Drug: Ondansetron 8mg or matched placebo Parkinson''s Hallucinations University College London|MODEPHARMA Limited|PARKINSONS UK|PRIMENT|SEALED ENVELOPE|Wasdell Packaging Ltd|Custom Pharmaceuticals Limited April 1 2020 Phase 2
NCT03785691 Recruiting Drug: Mirtazapine|Drug: Ondansetron|Drug: Placebo Hyperemesis Gravidarum|Nausea Gravidarum|Vomiting of Pregnancy Nordsjaellands Hospital|Bispebjerg Hospital|Aalborg University Hospital|Aarhus University Hospital|Herlev and Gentofte Hospital|Hvidovre University Hospital|Odense University Hospital|Rigshospitalet Denmark|Regionernes Medicinpulje|Kolding Sygehus March 1 2019 Phase 2
NCT03642964 Active not recruiting Drug: CTC-501 Major Depressive Disorder (MDD) Chase Therapeutics Corporation September 10 2018 Phase 2

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5-HT Receptor Signaling Pathway Map

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID