Ondansetron

Catalog No.S1996 Synonyms: GR 38032F, GR-C507/75

For research use only.

Ondansetron (GR 38032F, GR-C507/75) is a serotonin 5-HT3 receptor antagonist used mainly as an antiemetic.

Ondansetron Chemical Structure

CAS No. 99614-02-5

Selleck's Ondansetron has been cited by 1 Publication

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Purity & Quality Control

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Biological Activity

Description Ondansetron (GR 38032F, GR-C507/75) is a serotonin 5-HT3 receptor antagonist used mainly as an antiemetic.
Targets
5-HT3 [1]

Protocol (from reference)

Solubility (25°C)

In vitro

DMSO 0.1 mg/mL
(0.34 mM)
Water Insoluble
Ethanol Insoluble

Chemical Information

Molecular Weight 293.36
Formula

C18H19N3O

CAS No. 99614-02-5
Storage 3 years -20°C powder
2 years -80°C in solvent
Smiles CC1=NC=CN1CC2CCC3=C(C2=O)C4=CC=CC=C4N3C

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

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%DMSO %

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Clinical Trial Information

NCT Number Recruitment Interventions Conditions Sponsor/Collaborators Start Date Phases
NCT04226170 Recruiting Drug: DAS-001 Myasthenia Gravis DAS-MG Inc April 8 2021 Phase 2
NCT04610398 Recruiting Drug: Dexamethasone 4mg|Drug: NaCl 0.9% Pain Postoperative|Nausea Postoperative|Opioid Use Balgrist University Hospital March 11 2021 Phase 3

(data from https://clinicaltrials.gov, updated on 2022-01-17)

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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