Ondansetron

Catalog No.S1996 Synonyms: GR 38032F, GR-C507/75

Ondansetron Chemical Structure

Molecular Weight(MW): 293.36

Ondansetron is a serotonin 5-HT3 receptor antagonist used mainly as an antiemetic.

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Cited by 1 Publication

1 Customer Review

  • Mean (±SEM) cumulative 5-HT concentration–response curves in the absence and presence of 5-HT antagonists (n = >8). Responses are expressed as a percentage of the maximum response for each curve.

    Int J Urol, 2016, 23(11):946-951. Ondansetron purchased from Selleck.

Purity & Quality Control

Choose Selective 5-HT Receptor Inhibitors

Biological Activity

Description Ondansetron is a serotonin 5-HT3 receptor antagonist used mainly as an antiemetic.
Targets
5-HT3 [1]

Protocol

References

Solubility (25°C)

In vitro DMSO 0.1 mg/mL (0.34 mM)
Water Insoluble
Ethanol Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 293.36
Formula

C18H19N3O

CAS No. 99614-02-5
Storage powder
in solvent
Synonyms GR 38032F, GR-C507/75

Bio Calculators

Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

  • Mass
    Concentration
    Volume
    Molecular Weight

*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

  • C1
    V1
    C2
    V2

* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).

The Serial Dilution Calculator Equation

  • Serial Dilutions

  • Computed Result

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):
Molecular Weight Calculator

Molecular Weight Calculator

Enter the chemical formula of a compound to calculate its molar mass and elemental composition:

Total Molecular Weight: g/mol

Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2

Instructions to calculate molar mass (molecular weight) of a chemical compound:

To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.

Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Clinical Trial Information

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT03817970 Not yet recruiting Nephrotoxicity University of Colorado Denver|Memorial Sloan Kettering Cancer Center|Rutgers University|National Institute of General Medical Sciences (NIGMS) April 25 2019 Not Applicable
NCT03817970 Not yet recruiting Nephrotoxicity University of Colorado Denver|Memorial Sloan Kettering Cancer Center|Rutgers University|National Institute of General Medical Sciences (NIGMS) April 25 2019 Not Applicable
NCT03865290 Recruiting Indigestion|Diabetes Mellitus Mayo Clinic|National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) March 2019 Phase 2
NCT03851835 Not yet recruiting Acute Gastroenteritis|Viral Illness|Vomiting|Diarrhea University of Calgary|Canadian Institutes of Health Research (CIHR)|Women and Children''s Health Research Institute (WCHRI)|The Hospital for Sick Children|Children''s Hospital Research Institute of Manitoba|University of Manitoba|Université de Montréal|University of Ottawa|University of Alberta|Alberta Children''s Hospital Research Institute|University of Western Ontario Canada March 2019 Phase 3
NCT03809234 Recruiting Neuropathic Pain Washington University School of Medicine March 20 2019 Phase 1
NCT03785691 Recruiting Hyperemesis Gravidarum|Nausea Gravidarum|Vomiting of Pregnancy Nordsjaellands Hospital|Bispebjerg Hospital|Aalborg Universitetshospital|Aarhus University Hospital|Herlev and Gentofte Hospital|Hvidovre University Hospital|Odense University Hospital|Rigshospitalet Denmark|Regionernes Medicinpulje March 1 2019 Phase 2

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3

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5-HT Receptor Signaling Pathway Map

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID