Tolperisone HCl

For research use only.

Catalog No.S4200

Tolperisone HCl Chemical Structure

Molecular Weight(MW): 281.82

Tolperisone HCl is an ion channel blocker and centrally-acting muscle relaxant.

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USD 97 In stock
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Biological Activity

Description Tolperisone HCl is an ion channel blocker and centrally-acting muscle relaxant.
Targets
Sodium channel [1]
In vitro

Tolperisone reduces sodium and potassium permeability in the node of Ranvier of frogs, blocks calcium currents in snail neurons and inhibits current through heterologously expressed Nav1.6 channels. [1] Tolperisone hydrochloride represents an effective and safe treatment of painful reflex muscle spasm without the typical side effects of centrally active muscle relaxants. [2]

Protocol

Solubility (25°C)

In vitro DMSO 56 mg/mL (198.7 mM)
Water 56 mg/mL (198.7 mM)
Ethanol 56 mg/mL (198.7 mM)

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 281.82
Formula

C16H23NO.HCl

CAS No. 3644-61-9
Storage powder
in solvent
Synonyms N/A
Smiles Cl.CC(CN1CCCCC1)C(=O)C2=CC=C(C)C=C2

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Dilution Calculator

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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID