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Ionomycin calcium PKC activator

Name: Ionomycin calcium
Brand: Selleck Chemicals
SKU: E5794
Availability: InStock
Rating: 5 (1 reviews)

Cat.No.E5794

Ionomycin calcium (SQ23377 calcium) is a potent and selective calcium ionophore and an antibiotic produced by Streptomyces conglobatus. It is highly specific for divalent cations (Ca>Mg>Sr=Ba) and also promotes T cell activation and proliferation by inducing phosphoinositide hydrolysis and protein kinase C (PKC) activation, leading to IL-2 production and IL-2R expression.

Chemical Structure

Molecular Weight: 749.08

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SDS/MSDS
Datasheet

Related Targets	Akt Wnt/beta-catenin HSP ROCK Microtubule Associated Integrin Bcr-Abl Actin FAK Kinesin
Other PKC Inhibitors	Darovasertib (LXS196) PMA chemical (Phorbol 12-myristate 13-acetate) Enzastaurin Go 6983 Sotrastaurin (AEB071) Bisindolylmaleimide I (GF109203X) Go 6976 Bisindolylmaleimide IX (Ro 31-8220) Mesylate Ruboxistaurin (LY333531) Hydrochloride Rottlerin

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Chemical Information, Storage & Stability

Molecular Weight	749.08	Formula	C₄₁H₇₂O₉.Ca	Storage (From the date of receipt)	3 years-20°Cpowder
CAS No.	56092-82-1	Download SDF		Storage of Stock Solutions	1 year-80°Cin solvent 1 month-20°Cin solvent

Read more about storage stability stock solution CAS number

Mechanism of Action

References	[1] https://pubmed.ncbi.nlm.nih.gov/28319/ [2] https://pubmed.ncbi.nlm.nih.gov/2545785/

Clinical Trial Information

(data from https://clinicaltrials.gov, updated on 2026-05-11)

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date
NCT07570342	NOT_YET_RECRUITING	ICSI; Testicular Sperm Extraction in Azoospermic Patients; Male Infertility; PGT-A	ART Fertility Clinics LLC	2026-04-30
NCT06106412	UNKNOWN	Infertility, Female	Instituto Valenciano de Infertilidad, IVI VALENCIA	2024-01-01
NCT03678610	COMPLETED	Infertility	Ibn Sina Hospital	2018-09-25

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