CAS No. 56092-82-1
Chemical Structure
Check the
Ionomycin calcium
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Chemical Information
| IUPAC Name | calcium (4R,6S,8S,10Z,12R,14R,16E,18R,19R,20S,21S)-19,21-dihydroxy-22-[(2S,5S)-5-[(2R,5S)-5-[(1R)-1-hydroxyethyl]-5-methyloxolan-2-yl]-5-methyloxolan-2-yl]-4,6,8,12,14,18,20-heptamethyl-11-oxido-9-oxodocosa-10,16-dienoate | |
|---|---|---|
| CAS Number | 56092-82-1 | |
| Molecular Formula |
C41H72O9.Ca |
|
| Molecular Weight (MW) | 749.08 | |
| InChIKey | WKRWUYKLUMMAKG-WYGBAUISSA-L |
Biological Activity
Ionomycin calcium is a potent, selective calcium ionophore and polyether antibiotic produced by Streptomyces conglobatus that exhibits high specificity for divalent cations. By facilitating calcium influx across biological membranes, it stimulates phosphoinositide hydrolysis and activates protein kinase C (PKC) signaling pathways. These cellular events induce interleukin-2 (IL-2) production and IL-2 receptor (IL-2R) expression, thereby promoting T cell activation and lymphocyte proliferation. [1]
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Note: Technical data last updated: Sep 1, 2026.