Doxapram

For research use only.

Catalog No.S5257

1 publication

Doxapram Chemical Structure

CAS No. 309-29-5

Doxapram is a central respiratory stimulant with a brief duration of action. Doxapram is a selective TASK-1, TASK-3, TASK-1/TASK-3 heterodimeric channel inhibitor with EC50 of 410 nM, 37 μM, 9 μM, respectively.

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RMB 1204.72 In stock
RMB 2678.18 In stock
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Selleck's Doxapram has been cited by 1 publication

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Description Doxapram is a central respiratory stimulant with a brief duration of action. Doxapram is a selective TASK-1, TASK-3, TASK-1/TASK-3 heterodimeric channel inhibitor with EC50 of 410 nM, 37 μM, 9 μM, respectively.

Protocol

References

Solubility (25°C)

In vitro DMSO 75 mg/mL (198.14 mM)
Ethanol 75 mg/mL (198.14 mM)
Water Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 378.51
Formula

C24H30N2O2

CAS No. 309-29-5
Storage powder
in solvent
Synonyms N/A
Smiles CCN1CC(C(C1=O)(C2=CC=CC=C2)C3=CC=CC=C3)CCN4CCOCC4

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Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT03894189 Recruiting Drug: Doxapram Hydrochloride|Drug: Theophylline Weaning Failure Beni-Suef University May 2019 Not Applicable
NCT02421068 Completed -- Premature Birth Sinno H.P. Simons|ZonMw: The Netherlands Organisation for Health Research and Development|Leiden Amsterdam Centre for Drug Research (LACDR)|Dutch Knowledge Centre for Pediatric Pharmacotherapy (NKFK)|Centre for Human Drug Research Netherlands|Radboud University|Erasmus Medical Center August 2014 --
NCT00389909 Completed Drug: Doxapram Premature Infants|Apnea Jean Michel Hascoet|Maternite Regionale Universitaire November 2006 Phase 4

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Potassium Channel Signaling Pathway Map

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