Dolasetron

Catalog No.S5326 Synonyms: MDL-73147EF

For research use only.

Dolasetron(MDL-73147EF) is a highly specific and selective serotonin 5-HT3 receptor antagonist. It has minimal activity at other known serotonin receptors, and has low affinity for dopamine receptors.

Dolasetron Chemical Structure

CAS No. 115956-12-2

Purity & Quality Control

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Biological Activity

Description Dolasetron(MDL-73147EF) is a highly specific and selective serotonin 5-HT3 receptor antagonist. It has minimal activity at other known serotonin receptors, and has low affinity for dopamine receptors.

Protocol (from reference)

Solubility (25°C)

In vitro

Chemical Information

Molecular Weight 324.37
Formula

C19H20N2O3

CAS No. 115956-12-2
Storage 3 years -20°C powder
2 years -80°C in solvent
Smiles C1C2CC3CC(CC1N3CC2=O)OC(=O)C4=CNC5=CC=CC=C54

In vivo Formulation Calculator (Clear solution)

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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Molarity Calculator

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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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