Dolasetron Mesylate

Catalog No.S5679 Synonyms: Anzemet hydrate

Dolasetron Mesylate Chemical Structure

Molecular Weight(MW): 420.48

Dolasetron Mesylate is a serotonin 5-HT3 receptor antagonist used to treat nausea and vomiting following chemotherapy.

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Biological Activity

Description Dolasetron Mesylate is a serotonin 5-HT3 receptor antagonist used to treat nausea and vomiting following chemotherapy.

Protocol

References

Solubility (25°C)

In vitro DMSO 84 mg/mL (199.77 mM)
Water 28 mg/mL (66.59 mM)
Ethanol Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 420.48
Formula

C20H24N2O6S

CAS No. 115956-13-3
Storage powder
in solvent
Synonyms Anzemet hydrate

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Clinical Trial Information

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT02625181 Completed Postoperative Nausea and Vomiting Vanderbilt University|Vanderbilt University Medical Center July 2016 Not Applicable
NCT02625181 Completed Postoperative Nausea and Vomiting Vanderbilt University|Vanderbilt University Medical Center July 2016 Not Applicable
NCT02550119 Terminated Malignant Digestive System Neoplasm|Nausea and Vomiting University of Southern California|National Cancer Institute (NCI) April 19 2006 Not Applicable
NCT02550119 Terminated Malignant Digestive System Neoplasm|Nausea and Vomiting University of Southern California|National Cancer Institute (NCI) April 19 2006 Not Applicable
NCT00020657 Completed Nausea and Vomiting|Unspecified Adult Solid Tumor Protocol Specific Gary Morrow|National Cancer Institute (NCI)|University of Rochester July 2001 Phase 3
NCT00020657 Completed Nausea and Vomiting|Unspecified Adult Solid Tumor Protocol Specific Gary Morrow|National Cancer Institute (NCI)|University of Rochester July 2001 Phase 3

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5-HT Receptor Signaling Pathway Map

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID