Dolasetron Mesylate

Catalog No.S5679 Synonyms: Anzemet hydrate,MDL-73147EF

For research use only.

Dolasetron Mesylate (Anzemet hydrate,MDL-73147EF) is a serotonin 5-HT3 receptor antagonist used to treat nausea and vomiting following chemotherapy.

Dolasetron Mesylate Chemical Structure

CAS No. 115956-13-3

Purity & Quality Control

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Biological Activity

Description Dolasetron Mesylate (Anzemet hydrate,MDL-73147EF) is a serotonin 5-HT3 receptor antagonist used to treat nausea and vomiting following chemotherapy.

Protocol (from reference)

Solubility (25°C)

In vitro

Chemical Information

Molecular Weight 420.48
Formula

C20H24N2O6S

CAS No. 115956-13-3
Storage 3 years -20°C powder
2 years -80°C in solvent
Smiles CS(=O)(=O)O.C1C2CC3CC(CC1N3CC2=O)OC(=O)C4=CNC5=CC=CC=C54.O

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Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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Tech Support

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