Home Immunology & Inflammation Nrf2 inhibitor BI033

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BI033 Nrf2 inhibitor

Cat.No.E6514

BI033 is a selective inhibitor of BTB and CNC homology 1 (BACH1) specifically binds to BACH1's N-terminal with a Kd of 9.0 uM. It disrupts the BACH1–HDAC1 interaction, enhances H3K27 acetylation at BACH1 target genes, and upregulates angiogenic genes, suggesting its therapeutic potential for myocardial infarction and ischemic vascular disease.

Chemical Structure

Molecular Weight: 384.906

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Chemical Information, Storage & Stability

Molecular Weight 384.906 Formula

C21H25N5O3S

 Storage (From the date of receipt)
CAS No. 880810-80-0 -- Storage of Stock Solutions

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