CAS No. 880810-80-0
Chemical Structure
Check the
BI033
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Chemical Information
| CAS Number | 880810-80-0 | |
|---|---|---|
| Molecular Formula |
C21H25N5O3S |
|
| Molecular Weight (MW) | 384.906 |
Biological Activity
BI033 is a selective inhibitor of BTB and CNC homology 1 (BACH1) that specifically targets the N-terminal region of the transcription factor. By disrupting the interaction between BACH1 and HDAC1, BI033 enhances H3K27 acetylation at BACH1 target gene loci. This derepression promotes the expression of downstream angiogenic genes, highlighting the pathway's therapeutic potential in ischemic vascular disease and myocardial infarction. [1]
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Note: Technical data last updated: Sep 1, 2026.