Home Cytoskeletal Signaling Actin inhibitor - Microtubule Associated inhibitor Benproperine phosphate For research use only.

Benproperine phosphate

Synonyms: Blascorid, Pirexyl phosphate

Benproperine phosphate (Blascorid, Pirexyl), a cough suppressant, is an orally active, potent actin-related protein 2/3 complex subunit 2 (ARPC2) inhibitor. Benproperine phosphate attenuates the actin polymerization rate of action polymerization nucleation by impairing Arp2/3 function. Benproperine phosphate suppresses cancer cell migration and tumor metastasis.

Benproperine phosphate Chemical Structure

Benproperine phosphate Chemical Structure

CAS: 19428-14-9

Selleck's Benproperine phosphate has been cited by 1 publication

Purity & Quality Control

Batch: S525601 Water] 81 mg/mL] false] DMSO] 60 mg/mL] false] Ethanol] 3 mg/mL] false Purity: 99.85%
99.85

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Biological Activity

Description Benproperine phosphate (Blascorid, Pirexyl), a cough suppressant, is an orally active, potent actin-related protein 2/3 complex subunit 2 (ARPC2) inhibitor. Benproperine phosphate attenuates the actin polymerization rate of action polymerization nucleation by impairing Arp2/3 function. Benproperine phosphate suppresses cancer cell migration and tumor metastasis.

Chemical Information & Solubility

Molecular Weight 407.44 Formula

C21H27NO.H3O4P
CAS No. 19428-14-9 SDF --
Smiles CC(COC1=CC=CC=C1CC2=CC=CC=C2)N3CCCCC3.OP(=O)(O)O
Storage (From the date of receipt) 3 years -20°C powder

In vitro
Batch:

Water : 81 mg/mL

DMSO : 60 mg/mL ( (147.26 mM)； Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : 3 mg/mL


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In vivo
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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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