5a-Pregnane-3,20-dione

Catalog No.S3206 Synonyms: 5alphaP, 5-a-dihydroprogesterone, 3,20-allopregnanedione, 5-Alpha-Dihydro Progesterone

For research use only.

5a-Pregnane-3,20-dione (5alphaP, 5-a-dihydroprogesterone, 3,20-allopregnanedione, 5-Alpha-Dihydro Progesterone) is the endogenous progesterone metabolite. 5a-Pregnane-3,20-dione depolymerizes actin and decreases expression of actin and vinculin. 5a-Pregnane-3,20-dione is involved in promoting breast neoplasia and metastasis by affecting adhesion and cytoskeletal molecules.

5a-Pregnane-3,20-dione Chemical Structure

CAS No. 566-65-4

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Biological Activity

Description 5a-Pregnane-3,20-dione (5alphaP, 5-a-dihydroprogesterone, 3,20-allopregnanedione, 5-Alpha-Dihydro Progesterone) is the endogenous progesterone metabolite. 5a-Pregnane-3,20-dione depolymerizes actin and decreases expression of actin and vinculin. 5a-Pregnane-3,20-dione is involved in promoting breast neoplasia and metastasis by affecting adhesion and cytoskeletal molecules.
Targets
actin [1]
()
vinculin [1]
()

Protocol (from reference)

Solubility (25°C)

In vitro

Ethanol 3.5 mg/mL
(11.05 mM)
DMSO 3 mg/mL
(9.47 mM)
Water Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 316.48
Formula
C21H32O2
CAS No. 566-65-4
Storage 3 years -20°C powder
2 years -80°C in solvent

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