CAS No. 19428-14-9
Batch:
Purity:99.85
Chemical Structure
Check the
Benproperine phosphate
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | 1-[1-(2-benzylphenoxy)propan-2-yl]piperidine;phosphoric acid | |
|---|---|---|
| CAS Number | 19428-14-9 | |
| Molecular Formula |
C21H27NO.H3O4P |
|
| Molecular Weight (MW) | 407.44 | |
| SMILES | CC(COC1=CC=CC=C1CC2=CC=CC=C2)N3CCCCC3.OP(=O)(O)O | |
| InChIKey | MCVUURBOSHQXMK-UHFFFAOYSA-N |
Benproperine phosphate is an orally active, potent actin-related protein 2/3 complex subunit 2 (ARPC2) inhibitor. The compound impairs Arp2/3 complex-mediated actin dynamics, thereby decreasing the nucleation rate during actin polymerization. Through this targeted disruption of actin filament formation, benproperine phosphate suppresses downstream cellular motility, effectively inhibiting cancer cell migration and tumor metastasis. [1]
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Concentration
Volume
Mass
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Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| Water | 81 mg/mL |
| DMSO |
60 mg/mL
(147.26 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 3 mg/mL |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.