Amsacrine hydrochloride

Catalog No.S5627 Synonyms: m-AMSA, acridinyl anisidide

For research use only.

Amsacrine hydrochloride (m-AMSA, acridinyl anisidide) is the hydrochloride salt form of amsacrine, which is an inhibitor of topoisomerase II with antineoplastic activity.

Amsacrine hydrochloride Chemical Structure

CAS No. 54301-15-4

Purity & Quality Control

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Biological Activity

Description Amsacrine hydrochloride (m-AMSA, acridinyl anisidide) is the hydrochloride salt form of amsacrine, which is an inhibitor of topoisomerase II with antineoplastic activity.
Targets
Topo II [1]
()

Protocol (from reference)

Chemical Information

Molecular Weight 429.92
Formula

C21H20ClN3O3S

CAS No. 54301-15-4
Storage 3 years -20°C powder
2 years -80°C in solvent
Smiles COC1=C(C=CC(=C1)NS(=O)(=O)C)NC2=C3C=CC=CC3=NC4=CC=CC=C42.Cl

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Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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Molarity Calculator

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Clinical Trial Information

NCT Number Recruitment Interventions Conditions Sponsor/Collaborators Start Date Phases
NCT04997980 Recruiting Drug: Amiodarone Injection Out-Of-Hospital Cardiac Arrest IRCCS Policlinico S. Matteo|University of the Basque Country (UPV/EHU)|Oslo University Hospital|The Hospital of Vestfold January 1 2015 --

(data from https://clinicaltrials.gov, updated on 2022-01-17)

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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