Ofloxacin

Catalog No.S1463 Synonyms: DL8280

For research use only.

Ofloxacin (DL8280) is a synthetic broad-spectrum antimicrobial agent.

Ofloxacin Chemical Structure

CAS No. 82419-36-1

Purity & Quality Control

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Biological Activity

Description Ofloxacin (DL8280) is a synthetic broad-spectrum antimicrobial agent.
Targets
Topo II [1] Topoisomerase IV [1]

Protocol (from reference)

Solubility (25°C)

In vitro

Chemical Information

Molecular Weight 361.37
Formula

C18H20FN3O4

CAS No. 82419-36-1
Storage 3 years -20°C powder
2 years -80°C in solvent
Smiles CC1COC2=C3N1C=C(C(=O)C3=CC(=C2N4CCN(CC4)C)F)C(=O)O

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Clinical Trial Information

NCT Number Recruitment Interventions Conditions Sponsor/Collaborators Start Date Phases
NCT05441930 Not yet recruiting Drug: Levofloxacin Ocular Implant|Drug: Control Cataract PolyActiva Pty Ltd June 23 2022 Phase 1
NCT04239326 Recruiting Diagnostic Test: targeted Next Generation Sequencing (tNGS) Tuberculosis Multidrug-Resistant Foundation for Innovative New Diagnostics Switzerland April 16 2021 --
NCT05213156 Completed Drug: Oxatrex Dry Eye Disease University Hospital of Patras|University of Patras September 24 2019 Phase 4

(data from https://clinicaltrials.gov, updated on 2022-08-01)

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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