Neohesperidin

Catalog No.S2332 Synonyms: NSC 31048

For research use only.

Neohesperidin (NSC 31048), a flavanone glycoside found in citrus fruits, is an antioxidant agent.

Neohesperidin Chemical Structure

CAS No. 13241-33-3

Selleck's Neohesperidin has been cited by 4 Publications

Purity & Quality Control

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Biological Activity

Description Neohesperidin (NSC 31048), a flavanone glycoside found in citrus fruits, is an antioxidant agent.
In vitro

Neohesperidin, a flavanone glycoside found in citrus fruits, is an antioxidant agent. Neohesperidin is an antioxidant agent with an IC50 of 22.31 μg/ml in the 1,1-diphenyl-2-picryldydrazyl (DPPH) radical-scavenging assay. Neohesperidin (50 mg/kg) significantly inhibits HCl/ethanol-induced gastric lesions, and increases the mucus content. In pylorus ligated rats, neohesperidin (50 mg/kg) significantly decreases the volume of gastric secretion and gastric acid output, and increases the pH. [1] In addition, Neohesperidin inhibits the growth of Caco-2, CEM/ADR5000 and CCRF-CEM leukaemia cells with IC50 of 0.17, 0.17 and 0.12 mM, respectively. [2]

Protocol (from reference)

Solubility (25°C)

In vitro

Chemical Information

Molecular Weight 610.56
Formula

C28H34O15

CAS No. 13241-33-3
Storage 3 years -20°C powder
2 years -80°C in solvent
Smiles CC1C(C(C(C(O1)OC2C(C(C(OC2OC3=CC(=C4C(=O)CC(OC4=C3)C5=CC(=C(C=C5)OC)O)O)CO)O)O)O)O)O

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Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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