Home Immunology & Inflammation ROS inhibitor - NLR inhibitor Troxerutin

Troxerutin

Catalog No.S2369

For research use only.

Troxerutin, a natural bioflavonoid isolated from Sophora japonica, has been reported to have many benefits and medicinal properties. Troxerutin, also known as vitamin P4, is a tri-hydroxyethylated derivative of natural bioflavonoid rutins which can inhibit the production of reactive oxygen species (ROS) and depress ER stress-mediated NOD activation.

Troxerutin Chemical Structure

CAS No. 7085-55-4

Selleck's Troxerutin has been cited by 1 Publication

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Description Troxerutin, a natural bioflavonoid isolated from Sophora japonica, has been reported to have many benefits and medicinal properties. Troxerutin, also known as vitamin P4, is a tri-hydroxyethylated derivative of natural bioflavonoid rutins which can inhibit the production of reactive oxygen species (ROS) and depress ER stress-mediated NOD activation.
In vitro

Troxerutin (Trihydroxyethylrutin), a natural bioflavonoid isolated from Sophora japonica., has been reported to have many benefits and medicinal properties. Troxerutin reduces omocysteine, alpha-amino adipic acid, cholesterol, triglycerides, and LDL apo B levels in plasma of patients of acute myocardial infarction. [1] Troxerutin decreases erythrocyte aggregation and shows positive action on stasis, capillary perfusion and trophic complications of chronic venous insufficiency. [2] Troxerutin also attenuates cognitive impairment and oxidative stress induced by D-galactose in mouse brain through decreasing advanced glycation end products, reactive oxygen species and protein carbonyl levels and enhancing phosphoinositide 3-kinase/Akt activation. [3]

Protocol (from reference)

Solubility (25°C)

In vitro

Chemical Information

Molecular Weight 742.68
Formula

C33H42O19

CAS No. 7085-55-4
Storage 3 years -20°C powder
2 years -80°C in solvent
Smiles CC1C(C(C(C(O1)OCC2C(C(C(C(O2)OC3=C(OC4=CC(=CC(=C4C3=O)O)OCCO)C5=CC(=C(C=C5)OCCO)OCCO)O)O)O)O)O)O

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