Docetaxel

Catalog No.S1148 Synonyms: RP56976, NSC 628503

Docetaxel Chemical Structure

Molecular Weight(MW): 807.88

Docetaxel, an analog of paclitaxel, is an inhibitor of depolymerisation of microtubules by binding to stabilized microtubules.

Size Price Stock Quantity  
In DMSO USD 91 In stock
USD 70 In stock
USD 270 In stock
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Cited by 15 Publications

7 Customer Reviews

  • Immunohistochemistry and quantification of cleaved caspase 3 expression in DU145-DR tumor xenografts from (D). Scale bar, 100 mm. Data represent the mean ± SD. *p < 0.05.

    Cell, 2018, 174(5):1200-1215. Docetaxel purchased from Selleck.

  • J Transl Med 2013 0.6. Docetaxel purchased from Selleck.

  • J Transl Med 2013 0.6. Docetaxel purchased from Selleck.

  • Viability of cells after exposure to 0, 10, or 10,000 nM docetaxel, assessed by calcein-AM staining (green, left panels) and ethidium homodimer-1 (red, middle panels).

    Mol Pharmaceutics, 2014, 11: 2040−50. Docetaxel purchased from Selleck.

  • TNBC and non-TNBC cells were treated for 6 d with the specified concentrations of docetaxel (doc) alone, TTK inhibitor (TTKi) alone or the combinations. The survival of cells was measured using the MTS/MTA assay. ***P<0.001 comparing the combination with single agents and with non-TNBC cell lines.

    Oncogenesis, 2014, 3: e100 . Docetaxel purchased from Selleck.

  • Cell cycle study of percent cell populations in various phases after treatment with vehicle, HCI-2509 in increasing concentrations and docetaxel alone and in combination with HCI-2509 using (a) PC3 cells. Student's unpaired t-tests, using GraphPad Prism software, were used to calculate two-tailed P-values for each experiment to determine statistical significance between untreated and treated samples. The statistically significant P-values are labeled in each figure with an asterisk. (Replicated two more times, representative graph shown).

    Prostate Cancer Prostatic Dis, 2016, 19(4):349-357. Docetaxel purchased from Selleck.

  • Biomed Pharmacother, 2018, 99:445-450. Docetaxel purchased from Selleck.

Purity & Quality Control

Choose Selective Microtubule Associated Inhibitors

Biological Activity

Description Docetaxel, an analog of paclitaxel, is an inhibitor of depolymerisation of microtubules by binding to stabilized microtubules.
Targets
Microtubules [1]
(Cell-free assay)
In vitro

Docetaxel is a cytotoxic agent, especially for proliferating cells, which is related to its ability to promote the formation of microtubule bundles and induce sustained mitotic arrest, followed by apoptosis of mitotically arrested cells or permanent mitotic block. Docetaxel suppresses microtubule dynamic instability as well as tread-milling, resulting in the failure of chromosomes to segregate to the daughter cells, which in turn triggers premature exit from mitosis rather than a block at this phase of the cell cycle. [2] Docetaxel inhibits the clonogenic survival of Human cancer cell Hs746T (stomach), AGS (stomach), HeLa (cervix), CaSki (cervix), BxPC3 (pancreas), Capan-1 (pancreas) with IC50 of 1 nM, 1 nM, 0.3 nM, 0.3 nM, 0.3 nM and 0.3 nM respectively. [4] Docetaxel inhibits endothelial cell migration that does not affects microtubule gross morphology or inhibit cell proliferation, although they does produce more subtle effects on microtubule dynamics. Docetaxel inhibits HUVEC migration with an observed IC50 of 1 pM. HUVEC chemotaxis stimulated by either of two angiogenic factors, thymidine phosphorylase or VEGF, is inhibited by Docetaxel with IC 50 of 10 pM and is ablated at 1 nM. [7] Docetaxel induces human monocytes, but not RAW 264.7 murine macrophages, Prostaglandin H Synthase-2m (PGHS-2) expression. [8]

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
HSC-3 NGXsfIRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXHJR|UxRTBwMECwNVMzKM7:TR?= M3jDNXNCVkeHUh?=
5637 NHHtVIJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MX;JR|UxRTBwMECwNVQ{KM7:TR?= MnfmV2FPT0WU
HT-144 NVHhcFdUT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NX;YfXBKUUN3ME2wMlAxODF3NzFOwG0> NIe0enNUSU6JRWK=
NCI-H292 M1Sybmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mo[1TWM2OD1yLkCwNFE2QSEQvF2= MnL4V2FPT0WU
HCE-T NF\DOIhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXvJR|UxRTBwMECwNVYzKM7:TR?= MXLTRW5ITVJ?
ESS-1 NHL0SGpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M{PmXmlEPTB;MD6wNFAyPzlizszN NYHtTZFQW0GQR1XS
D-566MG MUfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NH7oZ2dKSzVyPUCuNFAxOTh{IN88US=> Mo\4V2FPT0WU
CAL-62 NIKyZlRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M17zXmlEPTB;MD6wNFAyQDVizszN MWLTRW5ITVJ?
GT3TKB Mn3JS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1zMb2lEPTB;MD6wNFAzOzJizszN M4S3XnNCVkeHUh?=
HSC-4 NWfkflI6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1T3Z2lEPTB;MD6wNFAzOzlizszN MXPTRW5ITVJ?
KOSC-2 NWeycnNoT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYPJR|UxRTBwMECwNlU2KM7:TR?= MWrTRW5ITVJ?
NB14 MXXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NX60PYE6UUN3ME2wMlAxODJ4IN88US=> NXewW45VW0GQR1XS
ES8 NEPafGZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVLJR|UxRTBwMECwNlYh|ryP NFLidIpUSU6JRWK=
BFTC-905 NYPpUYV{T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MW\JR|UxRTBwMECwNlY5KM7:TR?= MWHTRW5ITVJ?
A498 NFPhUmpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NEOzbm1KSzVyPUCuNFAxOjd6IN88US=> MV7TRW5ITVJ?
HO-1-N-1 MoLKS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3HDUmlEPTB;MD6wNFAzQDFizszN NEDY[VVUSU6JRWK=
SF539 M2nQTWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NEDYcnVKSzVyPUCuNFAxOzB{IN88US=> Mnj6V2FPT0WU
HuO-3N1 NVzK[WFXT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NU\CbYd1UUN3ME2wMlAxODNyMjFOwG0> MoDSV2FPT0WU
NCI-H510A MYHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M{Gy[mlEPTB;MD6wNFA{OzZizszN M4TXN3NCVkeHUh?=
CAL-27 NG\SeW5Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MlTvTWM2OD1yLkCwNFM{QSEQvF2= NVzuVpd3W0GQR1XS
TE-8 NFzMR3JIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXXneFZoUUN3ME2wMlAxODN4NjFOwG0> M17qfXNCVkeHUh?=
VA-ES-BJ M3Xoe2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NILuZYJKSzVyPUCuNFAxOzd3IN88US=> MkTYV2FPT0WU
RH-1 NW\3V5lvT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NIn1Z3FKSzVyPUCuNFAxOzh4IN88US=> NVryV5dIW0GQR1XS
COLO-800 Mlf3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFK3e2dKSzVyPUCuNFAxOzh6IN88US=> NFHw[ZRUSU6JRWK=
ES7 MX\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWnvcWVSUUN3ME2wMlAxODN6OTFOwG0> NIfnZmVUSU6JRWK=
GAMG M2jpbWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3e3SWlEPTB;MD6wNFA1OTZizszN NUPjZpFwW0GQR1XS
Ca9-22 MVzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXzJR|UxRTBwMECwOFI{KM7:TR?= M13jdHNCVkeHUh?=
SBC-1 MWXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGnLUlJKSzVyPUCuNFAxPDNizszN NWjGPGZDW0GQR1XS
RPMI-7951 MX\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXHTSJhXUUN3ME2wMlAxODR2ODFOwG0> MmfBV2FPT0WU
SW1710 MnXYS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MV;JR|UxRTBwMECwOFY3KM7:TR?= NWDTPXB2W0GQR1XS
HGC-27 M2\u[2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NECzeGZKSzVyPUCuNFAxPDdzIN88US=> MYfTRW5ITVJ?
MC-IXC MkTLS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVPJR|UxRTBwMECwOFc6KM7:TR?= MWDTRW5ITVJ?
FTC-133 NVK0Z3pWT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MWrJR|UxRTBwMECwOFg6KM7:TR?= Mmm3V2FPT0WU
HT-1080 NE[0XJpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFjPPYZKSzVyPUCuNFAxPTBzIN88US=> MmnLV2FPT0WU
NMC-G1 MVzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NF\4TJdKSzVyPUCuNFAxPTF5IN88US=> NFn5[VlUSU6JRWK=
GI-1 MUPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NImxOY1KSzVyPUCuNFAxPTJ6IN88US=> NH32O3dUSU6JRWK=
CGTH-W-1 NWLU[FFGT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlPOTWM2OD1yLkCwNFU1OiEQvF2= NUT5emZ4W0GQR1XS
A2058 NVvp[3pST3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3\ZNGlEPTB;MD6wNFA2PDRizszN Mo\FV2FPT0WU
ETK-1 NHfrZZhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MWDJR|UxRTBwMECwOVU5KM7:TR?= NWDMW2Q1W0GQR1XS
NEC8 NWrmOGV4T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHXqOpBKSzVyPUCuNFAxPTZzIN88US=> M{PoWnNCVkeHUh?=
TE-11 Ml;0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3HCfGlEPTB;MD6wNFA2PjlizszN NFz3b5NUSU6JRWK=
NCI-H720 NXTiZ4lbT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1PDcGlEPTB;MD6wNFA2QCEQvF2= NWOyfWRMW0GQR1XS
PSN1 NX:4cpJqT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Mm\uTWM2OD1yLkCwNFU5OSEQvF2= NGPTdnpUSU6JRWK=
SW780 MkPLS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MYfJR|UxRTBwMECwOVg4KM7:TR?= NXvGUpNxW0GQR1XS
8-MG-BA MXTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWLJR|UxRTBwMECwOVg6KM7:TR?= MUjTRW5ITVJ?
EC-GI-10 M2DsUGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NYLofVd3UUN3ME2wMlAxODV7MjFOwG0> MWrTRW5ITVJ?
SJSA-1 Mlf0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1PoZmlEPTB;MD6wNFA3OTVizszN NF\mb5lUSU6JRWK=
639-V NVHPSWlqT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MoXQTWM2OD1yLkCwNFY1PyEQvF2= NE\PNphUSU6JRWK=
PFSK-1 MYnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4OwbmlEPTB;MD6wNFA3PTdizszN MVLTRW5ITVJ?
DMS-273 NX6weIpLT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NGfT[G5KSzVyPUCuNFAxPjd2IN88US=> MXTTRW5ITVJ?
TE-9 M3m3eWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MmHyTWM2OD1yLkCwNFY4PiEQvF2= NH\LRVhUSU6JRWK=
SCC-25 MWDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3jPOmlEPTB;MD6wNFA3QCEQvF2= NFLEWYRUSU6JRWK=
PA-1 MkHDS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWTJR|UxRTBwMECwOlg4KM7:TR?= MWHTRW5ITVJ?
MHH-ES-1 MV\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYXJR|UxRTBwMECwO{DPxE1? NIfuTIJUSU6JRWK=
Daoy Mn3GS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MnjvTWM2OD1yLkCwNFch|ryP NWnLbZZRW0GQR1XS
G-402 M4roN2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{e5VmlEPTB;MD6wNFA4ODZizszN NELqVpRUSU6JRWK=
YKG-1 MkPNS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M17rfWlEPTB;MD6wNFA4ODdizszN MX\TRW5ITVJ?
Ca-Ski MlfES5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGrL[G1KSzVyPUCuNFAxPzJ6IN88US=> NHvGOIZUSU6JRWK=
CHP-212 M1rKPGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MkfKTWM2OD1yLkCwNFc{KM7:TR?= NEjhb2RUSU6JRWK=
SCC-4 M17YNmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NUDlXFR6UUN3ME2wMlAxODd|OTFOwG0> M2nGUHNCVkeHUh?=
EW-3 M{LOXmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1fmemlEPTB;MD6wNFA4PDVizszN M{f6cHNCVkeHUh?=
P12-ICHIKAWA MknTS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Ml3zTWM2OD1yLkCwNFc1PSEQvF2= M2f0dHNCVkeHUh?=
HSC-2 MmL0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1PyPWlEPTB;MD6wNFA4PTVizszN MYPTRW5ITVJ?
HN MoP2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXHJR|UxRTBwMECwO|U5KM7:TR?= MWrTRW5ITVJ?
LXF-289 MWHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MUTJR|UxRTBwMECwO|U5KM7:TR?= M3nuRnNCVkeHUh?=
ES1 NYPIPYp5T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NInFdIVKSzVyPUCuNFAxPzdizszN M2jEWHNCVkeHUh?=
NTERA-S-cl-D1 MW\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MVjJR|UxRTBwMECwO|c{KM7:TR?= M4W4bnNCVkeHUh?=
K5 M3TFSGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NVnsR294UUN3ME2wMlAxODd5ODFOwG0> MlHSV2FPT0WU
HOS Mo[5S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGr2cGRKSzVyPUCuNFAxPzh{IN88US=> NVXmZZJEW0GQR1XS
YH-13 M37ScWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{jSUGlEPTB;MD6wNFA4QTFizszN NGDQVHlUSU6JRWK=
SW954 MVTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MoPiTWM2OD1yLkCwNFgzOyEQvF2= Mn[2V2FPT0WU
KYSE-510 M1TQOGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWX5b25{UUN3ME2wMlAxODh2IN88US=> MVrTRW5ITVJ?
8505C NEXQbFdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NEL1XIhKSzVyPUCuNFAxQDV2IN88US=> MYjTRW5ITVJ?
A549 NWH3UHdqT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M33tT2lEPTB;MD6wNFA5QDJizszN NYqyT4lzW0GQR1XS
Detroit562 NV\VRno4T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVPyU2RNUUN3ME2wMlAxODlyMjFOwG0> MmezV2FPT0WU
ES5 M1T2NWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NF3kTFBKSzVyPUCuNFAxQTFizszN NH\IZlZUSU6JRWK=
KYSE-140 Moq1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXX4c|lWUUN3ME2wMlAxODl|MzFOwG0> NIjjTFVUSU6JRWK=
GMS-10 MVLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NG\0N4tKSzVyPUCuNFAxQTRzIN88US=> M2jqenNCVkeHUh?=
D-263MG NX\OOWdLT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHjIUIFKSzVyPUCuNFAxQTR5IN88US=> NWDJOWEzW0GQR1XS
BCPAP MYLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MkTnTWM2OD1yLkCwNFk1PyEQvF2= M2jHZXNCVkeHUh?=
CHL-1 MlThS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MlOwTWM2OD1yLkCwNFk2QCEQvF2= MnLsV2FPT0WU
RKO M3zLZ2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NVjhd2ZnUUN3ME2wMlAxODl6OTFOwG0> MlLyV2FPT0WU
SW48 MVrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4HwPWlEPTB;MD6wNFExOSEQvF2= MmfUV2FPT0WU
BPH-1 Mn:xS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MlzKTWM2OD1yLkCwNVAzKM7:TR?= M3XsNnNCVkeHUh?=
EFO-27 NF\JeZpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFvIS3JKSzVyPUCuNFAyODJizszN MYTTRW5ITVJ?
CAL-33 M{ntemdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4nteWlEPTB;MD6wNFExPCEQvF2= NYHkNW1pW0GQR1XS
NCI-H1792 NH7o[ndIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NF;B[pBKSzVyPUCuNFAyODRizszN MlrVV2FPT0WU
BB30-HNC M4DVbWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGLSe2JKSzVyPUCuNFAyODVizszN NWfaXnA4W0GQR1XS
VM-CUB-1 MkT0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXz2NVVPUUN3ME2wMlAxOTB3IN88US=> NXSyb3dLW0GQR1XS
TE-5 MXzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NEXZTI1KSzVyPUCuNFAyODZizszN NETufWNUSU6JRWK=
NB13 MoO1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MUjJR|UxRTBwMECxNFch|ryP NITFUIZUSU6JRWK=
NBsusSR M13Tdmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NETQSlVKSzVyPUCuNFAyOSEQvF2= MkDCV2FPT0WU
LNCaP-Clone-FGC NHjvV5RIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWG4NZVHUUN3ME2wMlAxOTFizszN MXHTRW5ITVJ?
EPLC-272H MWjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFTiSFhKSzVyPUCuNFAyOTFizszN NGHU[JNUSU6JRWK=
KNS-62 NUW1O3RnT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlfLTWM2OD1yLkCwNVEzKM7:TR?= MX3TRW5ITVJ?
RERF-LC-MS NXTpNYFTT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NXnuUZdiUUN3ME2wMlAxOTF|IN88US=> NYjpe4wzW0GQR1XS
LOXIMVI MUDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NI\xOYVKSzVyPUCuNFAyOTZizszN MXnTRW5ITVJ?
KINGS-1 MUPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmnpTWM2OD1yLkCwNVE4KM7:TR?= MVPTRW5ITVJ?
T98G NVPjfJpKT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MofzTWM2OD1yLkCwNVE4KM7:TR?= MlewV2FPT0WU
HCC1806 Mn[zS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MoD4TWM2OD1yLkCwNVE5KM7:TR?= MWDTRW5ITVJ?
MZ1-PC NWmycmc5T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVP0Umd2UUN3ME2wMlAxOTF6IN88US=> M{H4b3NCVkeHUh?=
RT-112 NHrRN4ZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXr2VIt2UUN3ME2wMlAxOTF7IN88US=> MWnTRW5ITVJ?
LK-2 NFj6O5BIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NH;DUZdKSzVyPUCuNFAyOjFizszN M4Pv[3NCVkeHUh?=
A375 MnO0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NUXrNHdQUUN3ME2wMlAxOTJzIN88US=> NE[1Wo1USU6JRWK=
SF268 MYrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGTVVZJKSzVyPUCuNFAyOjFizszN M{Xyc3NCVkeHUh?=
H9 NUfKcIw2T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NEHYbWtKSzVyPUCuNFAyOjRizszN M2G5XXNCVkeHUh?=
KYSE-410 M1jRUmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3XDcWlEPTB;MD6wNFEzPCEQvF2= NFPCc5dUSU6JRWK=
G-401 MkjZS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MX7JR|UxRTBwMECxNlch|ryP NY\nPWpzW0GQR1XS
SW982 MkD0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MnjHTWM2OD1yLkCwNVI4KM7:TR?= NGTzeYFUSU6JRWK=
D-423MG M4TwdWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MoH3TWM2OD1yLkCwNVMh|ryP MV3TRW5ITVJ?
CAMA-1 NIfPSmxIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXTBWVlqUUN3ME2wMlAxOTNzIN88US=> M33CeHNCVkeHUh?=
SCC-9 MXjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MVHJR|UxRTBwMECxN|Ih|ryP MV\TRW5ITVJ?
SAS MXPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Ml;uTWM2OD1yLkCwNVM1KM7:TR?= MofDV2FPT0WU
KYSE-180 NInw[JJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NE\JV|lKSzVyPUCuNFAyOzVizszN M1PFXnNCVkeHUh?=
EW-16 NXjxfZZzT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHHkclNKSzVyPUCuNFAyOzVizszN MYHTRW5ITVJ?
HD-MY-Z M2PzfGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NETiOWtKSzVyPUCuNFAyPDFizszN NFWy[mFUSU6JRWK=
KYSE-450 MmnoS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M{\3ZWlEPTB;MD6wNFE1OyEQvF2= MXjTRW5ITVJ?
LCLC-97TM1 NV3tZY0{T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUf1clZsUUN3ME2wMlAxOTR2IN88US=> MWnTRW5ITVJ?
KS-1 NI\RcFNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVjON|VHUUN3ME2wMlAxOTR2IN88US=> NGjNeFJUSU6JRWK=
TI-73 MmnTS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NW\hS|QzUUN3ME2wMlAxOTR2IN88US=> NXO1NIVYW0GQR1XS
A427 MX;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4PHfWlEPTB;MD6wNFE1QCEQvF2= MYjTRW5ITVJ?
LB831-BLC MnO1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MYjJR|UxRTBwMECxOFgh|ryP MkKxV2FPT0WU
MG-63 Mmj6S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1G3OmlEPTB;MD6wNFE2OSEQvF2= MonWV2FPT0WU
PANC-03-27 M1;TXWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXHJR|UxRTBwMECxOVQh|ryP MXTTRW5ITVJ?
23132-87 NIDOU5BIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWSxTZpIUUN3ME2wMlAxOTV3IN88US=> MV7TRW5ITVJ?
ES4 M134W2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MlnLTWM2OD1yLkCwNVU2KM7:TR?= MmfTV2FPT0WU
KP-4 MU\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWLJR|UxRTBwMECxOVYh|ryP MX;TRW5ITVJ?
NCI-H1703 M2G2UWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NELtVYZKSzVyPUCuNFAyPTdizszN MkPwV2FPT0WU
MCF7 M2n5cmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NX[4eFZzUUN3ME2wMlAxOTZzIN88US=> MmXJV2FPT0WU
A172 MUXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXTJR|UxRTBwMECxOlMh|ryP MX\TRW5ITVJ?
CAL-39 M1zHcWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWnVOJRqUUN3ME2wMlAxOTZ|IN88US=> MmPFV2FPT0WU
Saos-2 M3K3cGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWTPfoFuUUN3ME2wMlAxOTZ6IN88US=> MlnnV2FPT0WU
EW-11 NYSyS4ZVT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MVvJR|UxRTBwMECxOlkh|ryP MVvTRW5ITVJ?
D-336MG MoLLS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MmP6TWM2OD1yLkCwNVY6KM7:TR?= NVXtdoVwW0GQR1XS
SW13 M4D6XWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MWHJR|UxRTBwMECxOlkh|ryP NHLXNW5USU6JRWK=
ME-180 M{fnR2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHrpWIZKSzVyPUCuNFAyPjlizszN Mme0V2FPT0WU
SK-MEL-2 MknYS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MnfDTWM2OD1yLkCwNVch|ryP NGXIcldUSU6JRWK=
697 M2nqZ2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NX20TYx7UUN3ME2wMlAxOTd{IN88US=> Mk\nV2FPT0WU
D-247MG MYHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MX\JR|UxRTBwMECxO|Mh|ryP M{joSXNCVkeHUh?=
EoL-1-cell M324N2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NYnoeZMxUUN3ME2wMlAxOTd|IN88US=> MmfVV2FPT0WU
MV-4-11 NHfLboRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3jpTGlEPTB;MD6wNFE4PCEQvF2= MnnIV2FPT0WU
U-2-OS MkXpS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MlnhTWM2OD1yLkCwNVc2KM7:TR?= MWTTRW5ITVJ?
NCI-H526 MoO2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXfVT5E3UUN3ME2wMlAxOTd4IN88US=> MYrTRW5ITVJ?
SK-NEP-1 MXnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3r0fmlEPTB;MD6wNFE4PiEQvF2= M3vKUHNCVkeHUh?=
DB NWO4TG4xT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MVjJR|UxRTBwMECxO|gh|ryP MWrTRW5ITVJ?
GCT M2LuOmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NUjqT5piUUN3ME2wMlAxOThizszN NELUTo9USU6JRWK=
HCT-116 M121S2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NU[2WnRUUUN3ME2wMlAxOThzIN88US=> NGHMXmZUSU6JRWK=
AU565 MYTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MofjTWM2OD1yLkCwNVgyKM7:TR?= MU\TRW5ITVJ?
KALS-1 NVm1VWc1T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Mkm0TWM2OD1yLkCwNVgyKM7:TR?= NX7IW|JPW0GQR1XS
C2BBe1 MXvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmLTTWM2OD1yLkCwNVgzKM7:TR?= NFvSNI5USU6JRWK=
Becker NVm0W|d[T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3HmUmlEPTB;MD6wNFE5OyEQvF2= NX\TUY5jW0GQR1XS
647-V M1zDOWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYDJR|UxRTBwMECxPFQh|ryP M1vVfnNCVkeHUh?=
NCI-H2122 NXviNJNpT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Ml\aTWM2OD1yLkCwNVg1KM7:TR?= MX7TRW5ITVJ?
SBC-5 Mo\GS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MoL6TWM2OD1yLkCwNVg4KM7:TR?= NVfnWHR5W0GQR1XS
NB17 MkD1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NEjTdmVKSzVyPUCuNFAyQDlizszN MlX4V2FPT0WU
MHH-PREB-1 NYqwb4ZwT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2nFNGlEPTB;MD6wNFE5QSEQvF2= MUfTRW5ITVJ?
M14 NWLqT2NMT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NXriTnJMUUN3ME2wMlAxOTlzIN88US=> M2LKVHNCVkeHUh?=
NCI-H1048 M4jjeWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MWfJR|UxRTBwMECxPVIh|ryP NUnKPVJ5W0GQR1XS
CTB-1 M1jwdmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MWnJR|UxRTBwMECxPVIh|ryP NUX3c5NoW0GQR1XS
SK-PN-DW NF73cItIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MX\JR|UxRTBwMECxPVQh|ryP Mn[yV2FPT0WU
H4 MX;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGrleJBKSzVyPUCuNFAyQTZizszN NEn2RWVUSU6JRWK=
NCI-SNU-1 M3e2Nmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2HhVWlEPTB;MD6wNFE6PyEQvF2= MkTCV2FPT0WU
M059J NVX1PYF6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1fMWGlEPTB;MD6wNFE6QCEQvF2= NGnidmtUSU6JRWK=
OVCAR-5 MojXS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVjMeo9[UUN3ME2wMlAxOTl7IN88US=> MVLTRW5ITVJ?
SK-MEL-28 NIfKXYZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXPJR|UxRTBwMECyNFMh|ryP MWDTRW5ITVJ?
PC-14 NFvIRZdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NX7uNWp[UUN3ME2wMlAxOjB7IN88US=> NWf6e4p7W0GQR1XS
OVCAR-8 M1zDUWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Ml3LTWM2OD1yLkCwNlEzKM7:TR?= NGmzPXVUSU6JRWK=
BB49-HNC MUXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3X1WGlEPTB;MD6wNFIyOiEQvF2= NVjvdVJLW0GQR1XS
EFM-19 M{nqWGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3PLSGlEPTB;MD6wNFIyPSEQvF2= NXztSlNrW0GQR1XS
BHY MY\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MUDJR|UxRTBwMECyNVYh|ryP NGPXW5RUSU6JRWK=
SW756 Mn3RS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NH;tVZpKSzVyPUCuNFAzOTZizszN MoPFV2FPT0WU
TE-1 NH2xd5pIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M{jISGlEPTB;MD6wNFIyPiEQvF2= MoXaV2FPT0WU
NCI-H2452 M{\YdGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NIjGOVhKSzVyPUCuNFAzOTZizszN MVPTRW5ITVJ?
NCI-H1581 NXHMOWxRT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1rQN2lEPTB;MD6wNFIyPyEQvF2= NEDIfHpUSU6JRWK=
COR-L23 NHnIcJlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2fOOGlEPTB;MD6wNFIzKM7:TR?= NFTjOpVUSU6JRWK=
RXF393 MYHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVKxdZRHUUN3ME2wMlAxOjJ{IN88US=> MmHEV2FPT0WU
BFTC-909 MWjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWrJR|UxRTBwMECyNlUh|ryP MXzTRW5ITVJ?
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NCI-H650 NX3wSJhtT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4LlVWlEPTB;MD6wNFIzPSEQvF2= Mnv6V2FPT0WU
SK-UT-1 NEjG[2hIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1XMRWlEPTB;MD6wNFIzPiEQvF2= MlXyV2FPT0WU
GOTO NYnrdIQ6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1naRWlEPTB;MD6wNFIzPyEQvF2= NF\kSWZUSU6JRWK=
TYK-nu MmHaS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MkLkTWM2OD1yLkCwNlMzKM7:TR?= Mn;zV2FPT0WU
JVM-3 M3e1UWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MWTJR|UxRTBwMECyN|Mh|ryP MXHTRW5ITVJ?
SK-MES-1 NVv0fWlvT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFHqd4ZKSzVyPUCuNFAzOzNizszN NWPUUHVDW0GQR1XS
SK-HEP-1 MYDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MkjqTWM2OD1yLkCwNlM1KM7:TR?= MVXTRW5ITVJ?
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A673 NUPpTlZIT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Mn:2TWM2OD1yLkCwNlM2KM7:TR?= NHnWW5hUSU6JRWK=
NCI-H446 NH7FdpJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2PTbWlEPTB;MD6wNFI1OyEQvF2= Mmi3V2FPT0WU
RPMI-2650 NV;TPZd6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{L3fGlEPTB;MD6wNFI1PiEQvF2= M1HY[HNCVkeHUh?=
HCE-4 NFWzZ5FIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MlrETWM2OD1yLkCwNlQ4KM7:TR?= MXLTRW5ITVJ?
KGN NGPX[HJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M13jXGlEPTB;MD6wNFI1PyEQvF2= MVPTRW5ITVJ?
U251 NYDlTIZyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MWPJR|UxRTBwMECyOUDPxE1? NULVc2c6W0GQR1XS
BxPC-3 MWnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MVvJR|UxRTBwMECyOVEh|ryP NU[3c4dxW0GQR1XS
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TE-10 NEHBZnJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MUjJR|UxRTBwMECyOVQh|ryP MlH1V2FPT0WU
OC-314 M323Omdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MmD0TWM2OD1yLkCwNlU3KM7:TR?= NHz3PHlUSU6JRWK=
NCI-H1437 M1fwZ2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWS1W4NqUUN3ME2wMlAxOjZizszN MmXtV2FPT0WU
SNU-387 NFzkblZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NUPGZ5lnUUN3ME2wMlAxOjZzIN88US=> NXjQSWtlW0GQR1XS
A388 Mk\iS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M{DYVGlEPTB;MD6wNFI3PSEQvF2= MYTTRW5ITVJ?
C-33-A MlTOS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFvsfGRKSzVyPUCuNFAzPjZizszN MUHTRW5ITVJ?
CAL-51 MULHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NUDvZ4hsUUN3ME2wMlAxOjdzIN88US=> NFTpOJhUSU6JRWK=
Hs-578-T MnXmS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGPhdmJKSzVyPUCuNFAzPzJizszN MoLwV2FPT0WU
MDA-MB-415 NV;pXY94T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Mn7UTWM2OD1yLkCwNlc1KM7:TR?= NIjDVmFUSU6JRWK=
SW1417 NFHs[JpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NX[zWVRTUUN3ME2wMlAxOjd4IN88US=> M3vCR3NCVkeHUh?=
HCC70 NGTwU2lIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWLKXYdOUUN3ME2wMlAxOjd5IN88US=> MV7TRW5ITVJ?
ES3 NVu3UmpvT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Ml;oTWM2OD1yLkCwNlc4KM7:TR?= NIDDUm1USU6JRWK=
KYSE-270 Ml[wS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MmGyTWM2OD1yLkCwNlc5KM7:TR?= M4fWfXNCVkeHUh?=
HT-29 NV[4W4VCT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2PFc2lEPTB;MD6wNFI5KM7:TR?= NHnm[JRUSU6JRWK=
MDA-MB-361 Ml\XS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXvJR|UxRTBwMECyPFEh|ryP MWXTRW5ITVJ?
RPMI-8866 MYjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M132XGlEPTB;MD6wNFI5OSEQvF2= NGKxXXZUSU6JRWK=
JEG-3 M4O1Smdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVfJR|UxRTBwMECyPFIh|ryP MWDTRW5ITVJ?
HT-3 MYPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NH7oenNKSzVyPUCuNFAzQDJizszN NFz4Z3FUSU6JRWK=
HTC-C3 M{XyR2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MV\JR|UxRTBwMECyPFUh|ryP MmDpV2FPT0WU
NCI-H209 NX\zN41CT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYLrNGJXUUN3ME2wMlAxOjh4IN88US=> NY\Ibm4zW0GQR1XS
SKG-IIIa NF;pTJZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2rZZ2lEPTB;MD6wNFI5PiEQvF2= MWPTRW5ITVJ?
SW962 NHX4PIhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NH;GeWhKSzVyPUCuNFAzQTNizszN M{\3[3NCVkeHUh?=
LCLC-103H MkDvS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXvGcnhjUUN3ME2wMlAxOjl|IN88US=> NV\FUXZUW0GQR1XS
DOK M{i0N2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4LFXWlEPTB;MD6wNFI6PCEQvF2= NXm4[mxUW0GQR1XS
SW1088 MVXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHnGcI5KSzVyPUCuNFAzQTVizszN NFnueXZUSU6JRWK=
GP5d NW\mTWZLT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NI\VS2NKSzVyPUCuNFAzQTZizszN MorBV2FPT0WU
EW-1 Mn3KS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NWfTZZllUUN3ME2wMlAxOjl6IN88US=> NX3reII3W0GQR1XS
CP66-MEL M3ftcGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MY\JR|UxRTBwMECzJO69VQ>? MmHaV2FPT0WU
DEL MXfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NUHPUYQ2UUN3ME2wMlAxOzBzIN88US=> NYO2[3dvW0GQR1XS
DU-4475 MnHOS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mk\zTWM2OD1yLkCwN|AzKM7:TR?= NILHRlhUSU6JRWK=
HEC-1 M3HHWGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MUjJR|UxRTBwMECzNFMh|ryP M2XT[XNCVkeHUh?=
U031 NG\Ub|FIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MmrKTWM2OD1yLkCwN|A4KM7:TR?= MnLEV2FPT0WU
BB65-RCC NXnCVnBIT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUTYeZljUUN3ME2wMlAxOzB6IN88US=> MnLDV2FPT0WU
NUGC-3 M17Mcmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1nSZ2lEPTB;MD6wNFMxQCEQvF2= M1jkd3NCVkeHUh?=
IST-SL1 NGCzZlJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYjCXHUxUUN3ME2wMlAxOzF{IN88US=> NEHyUVhUSU6JRWK=
LS-411N M1H1Rmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NVPaWWZxUUN3ME2wMlAxOzF2IN88US=> MkXNV2FPT0WU
22RV1 NFm0W2ZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3:3TWlEPTB;MD6wNFMyPSEQvF2= MkPiV2FPT0WU
MKN28 M3fNWGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MojpTWM2OD1yLkCwN|E4KM7:TR?= MUDTRW5ITVJ?
ONS-76 MXvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1PreWlEPTB;MD6wNFMzOiEQvF2= Mk\CV2FPT0WU
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OCUB-M M4n0U2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2jkWWlEPTB;MD6wNFQ{QCEQvF2= NX3qcnpZW0GQR1XS
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LN-405 MoXGS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NYX3SYV[UUN3ME2wMlAxPDh{IN88US=> M{DhcXNCVkeHUh?=
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RPMI-8226 NVvU[WdmT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnTTTWM2OD1yLkCwOFk4KM7:TR?= MYTTRW5ITVJ?
KYSE-150 NEnrXHVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mk\YTWM2OD1yLkCwOFk6KM7:TR?= M{HaVXNCVkeHUh?=
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Mewo MnnTS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NX63[3JpUUN3ME2wMlAxPTB3IN88US=> NVrURnJXW0GQR1XS
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SK-N-AS MV\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVHyR|VkUUN3ME2wMlAxPTN3IN88US=> M2fGZnNCVkeHUh?=
NCI-H1651 NIC5XGZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MYfJR|UxRTBwMEC1OEDPxE1? MkLyV2FPT0WU
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KY821 NH;Lc|lIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXW5XotIUUN3ME2wMlAxPTVzIN88US=> MVfTRW5ITVJ?
SW1573 NHnGOGVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M{T4PGlEPTB;MD6wNFU2PCEQvF2= MU\TRW5ITVJ?
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MPP-89 NFTjcHNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MWnJR|UxRTBwMEC1Olch|ryP MXfTRW5ITVJ?
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SW1783 Mn65S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1P5NmlEPTB;MD6wNFU4KM7:TR?= Mmr3V2FPT0WU
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HCC38 NGjF[JJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MonNTWM2OD1yLkCwOkDPxE1? NF\KSZZUSU6JRWK=
NCI-H1648 NF:zSpdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M{TRdGlEPTB;MD6wNFYxOSEQvF2= MVTTRW5ITVJ?
NCI-H1573 M{fBVGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXnre2FqUUN3ME2wMlAxPjB5IN88US=> M3fLb3NCVkeHUh?=
MFM-223 Mn\tS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MX\JR|UxRTBwMEC2NVYh|ryP NGPkVHNUSU6JRWK=
NCI-H810 M1jjOmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NEDXZWRKSzVyPUCuNFA3OjJizszN MUXTRW5ITVJ?
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D-283MED MkD2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NX3GVpdPUUN3ME2wMlAxPjJ2IN88US=> MXfTRW5ITVJ?
NCI-H1755 NXjaR2ZnT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NX3i[VRLUUN3ME2wMlAxPjJ2IN88US=> M2rKPXNCVkeHUh?=
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MZ2-MEL MmLqS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2HjRmlEPTB;MD6wNFY2QCEQvF2= M1PSb3NCVkeHUh?=
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DMS-114 MYTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnuwTWM2OD1yLkCwOlk3KM7:TR?= M3f5bXNCVkeHUh?=
KYSE-520 MVXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M170SGlEPTB;MD6wNFch|ryP MY\TRW5ITVJ?
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COLO-829 M3flS2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MkTNTWM2OD1yLkCwO|I2KM7:TR?= NGDHSGtUSU6JRWK=
NCI-H2052 NH3MfWdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M{nJemlEPTB;MD6wNFczPyEQvF2= NF7wPGpUSU6JRWK=
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NCI-H2087 NF[wdYZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVz0fW1GUUN3ME2wMlAxPzR6IN88US=> NHPYbYdUSU6JRWK=
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NCI-H2126 NXW4dYx2T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NXvlUoZ2UUN3ME2wMlAxPzd|IN88US=> NWm3NmJYW0GQR1XS
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COLO-668 NXTCVo9pT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MWXJR|UxRTBwMEO4PFch|ryP MU\TRW5ITVJ?
LU-65 MW\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3fLOGlEPTB;MD6wN|kxPCEQvF2= NYO1e4MzW0GQR1XS
NB6 NG\lc|NIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MoHQTWM2OD1yLkCzPVUzKM7:TR?= Ml7ZV2FPT0WU
HT MYXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MU\JR|UxRTBwMESwNFch|ryP NG\ON4VUSU6JRWK=
COLO-684 NVS3PG5WT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4WwT2lEPTB;MD6wOFA6PSEQvF2= Moj3V2FPT0WU
NCI-H1693 NV\zUnJVT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NF3HR|dKSzVyPUCuNFQ{ODVizszN M3HsW3NCVkeHUh?=
LAN-6 NH;VUItIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFOxXHdKSzVyPUCuNFQ{OzVizszN MWHTRW5ITVJ?
MDA-MB-175-VII NYT4W5JIT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHLxT4dKSzVyPUCuNFQ1OTdizszN NEfWeI5USU6JRWK=
KMOE-2 NFHYZldIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3vLS2lEPTB;MD6wOFQ3QSEQvF2= NE\ZN4pUSU6JRWK=
DMS-79 MXHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHu2O4NKSzVyPUCuNFQ2PzlizszN MkTqV2FPT0WU
MHH-NB-11 MWjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M{\LZWlEPTB;MD6wOFYyPCEQvF2= MmLaV2FPT0WU
NCI-H69 MkD5S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVjLW3B5UUN3ME2wMlA1QDR7IN88US=> MVPTRW5ITVJ?
KE-37 NVG3UZZxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXfJR|UxRTBwMEWwNUDPxE1? NUH4XGV4W0GQR1XS
Ramos-2G6-4C10 MY\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWTJR|UxRTBwMEWwOlch|ryP NYr1fIprW0GQR1XS
NCI-H1793 NG\jRnJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXXJR|UxRTBwMEWwPVMh|ryP Mk\YV2FPT0WU
HT-1376 MXXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MV3JR|UxRTBwMEWxPFYh|ryP NWXQPXFYW0GQR1XS
EKVX M1fzWWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NIOwWJdKSzVyPUCuNFU{QDRizszN NVvKeplDW0GQR1XS
Capan-2 M4Py[Gdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHHrV5JKSzVyPUCuNFU{QTZizszN MUTTRW5ITVJ?
DoTc2-4510 M{\tc2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXfXPWhkUUN3ME2wMlA2PDR4IN88US=> NEfXTG9USU6JRWK=
UACC-893 MmmxS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MlrNTWM2OD1yLkC1OFYzKM7:TR?= MkPmV2FPT0WU
SK-MEL-3 NGPLRlJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWjxSmhuUUN3ME2wMlA2Pzh6IN88US=> MlzDV2FPT0WU
SK-MEL-1 NVu4OZpMT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVrIdpJqUUN3ME2wMlA2QCEQvF2= NWO5XHJYW0GQR1XS
SW948 MXLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVzUWYJVUUN3ME2wMlA2QTl4IN88US=> NHrFUllUSU6JRWK=
P30-OHK NGr2c4hIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MomxTWM2OD1yLkC2NVY4KM7:TR?= NFXOc2RUSU6JRWK=
NH-12 NIPwR4dIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWnaTIxoUUN3ME2wMlA3OjR2IN88US=> MnvaV2FPT0WU
KU-19-19 MV7Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MVrJR|UxRTBwME[zOlEh|ryP M4\JZXNCVkeHUh?=
A431 M1\Kc2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M165eWlEPTB;MD6wOlM4PCEQvF2= NFOzU2VUSU6JRWK=
NCI-H2405 NG\3bFdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWLXTmdqUUN3ME2wMlA3Ozh|IN88US=> NYixcFRmW0GQR1XS
KARPAS-299 MmOxS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFfDb|lKSzVyPUCuNFY2QDJizszN MYTTRW5ITVJ?
BALL-1 M4TtZmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXL3cZNQUUN3ME2wMlA3Pjd2IN88US=> NIHp[3RUSU6JRWK=
KURAMOCHI Mk\xS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFHqSlFKSzVyPUCuNFcxPzNizszN NEHydHBUSU6JRWK=
LS-1034 Mk\WS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MULJR|UxRTBwMEezOlkh|ryP NUjtWZg6W0GQR1XS
MFE-280 MnnjS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXfJR|UxRTBwMEe1N|Yh|ryP MnvDV2FPT0WU
HOP-62 MnTNS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NX;WUHZRUUN3ME2wMlA4Pjd4IN88US=> MVXTRW5ITVJ?
KG-1 NWLkT|RzT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2\NWGlEPTB;MD6wO|c5PyEQvF2= NVzkRYxRW0GQR1XS
CW-2 NHO2S5ZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NISzZ2ZKSzVyPUCuNFc5OzJizszN NF;WVplUSU6JRWK=
SW837 M3y4Omdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Ml3ZTWM2OD1yLkC4N|QzKM7:TR?= NXm3NpFKW0GQR1XS
MFH-ino Mmj3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NIT0ZmhKSzVyPUCuNFg2ODFizszN NW\QdlZZW0GQR1XS
HCC1419 M4np[Wdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYHJR|UxRTBwMEi5PFch|ryP Mn2wV2FPT0WU
HMV-II MUjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3HDdGlEPTB;MD6wPVAyKM7:TR?= MVHTRW5ITVJ?
BEN M2fJNmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M33nSGlEPTB;MD6wPVM5PSEQvF2= NFrWTYZUSU6JRWK=
SK-N-FI NGTKUVNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M175cWlEPTB;MD6wPVU2PiEQvF2= M4XacXNCVkeHUh?=
JVM-2 MYTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXzGTFN{UUN3ME2wMlA6PzF4IN88US=> NHrjVIlUSU6JRWK=
CAL-54 Ml\KS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVHJR|UxRTBwMUCwOEDPxE1? NIrOVnRUSU6JRWK=
T84 NITWWItIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mm\QTWM2OD1yLkGwPVUzKM7:TR?= M12yV3NCVkeHUh?=
SHP-77 NYnCcZJZT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXrJR|UxRTBwMUG2OFEh|ryP M3eyVnNCVkeHUh?=
G-361 MoLWS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWHJR|UxRTBwMUKzNlQh|ryP MX\TRW5ITVJ?
Calu-3 NVLJcFJOT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVf5UYVIUUN3ME2wMlE{QDF4IN88US=> MXnTRW5ITVJ?
HCC1937 M4j6fGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFzO[HJKSzVyPUCuNVQ6OzdizszN NEXnblZUSU6JRWK=
KM-H2 MXLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M360TGlEPTB;MD6xOVAyKM7:TR?= MYnTRW5ITVJ?
769-P MXfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mk\iTWM2OD1yLkG1PFQ{KM7:TR?= M1jTc3NCVkeHUh?=
NCI-H1304 MmfCS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NF3hSXNKSzVyPUCuNVYxPjFizszN MomxV2FPT0WU
D-542MG MlntS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MkmyTWM2OD1yLkG2Nlc5KM7:TR?= M1m5PHNCVkeHUh?=
ATN-1 MlHwS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NIPDeY9KSzVyPUCuNVc1PDFizszN M13Z[3NCVkeHUh?=
NCI-H2029 MX3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NUfoOmFbUUN3ME2wMlIxOjR|IN88US=> NHTTPYNUSU6JRWK=
ZR-75-30 NELRTm1Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MV;JR|UxRTBwMkC2OFMh|ryP M3XSSHNCVkeHUh?=
SW1116 NXm0b2kzT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWHLdnY2UUN3ME2wMlIyOTF5IN88US=> NFn1doZUSU6JRWK=
CCRF-CEM MXnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4q5XmlEPTB;MD6yO|YyPCEQvF2= NFvNZndUSU6JRWK=
LU-135 NWXlXGx6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NU\qPFB4UUN3ME2wMlI4PzN7IN88US=> MmnIV2FPT0WU
MC116 NGrNPZRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NUXyTmx5UUN3ME2wMlI5OzB7IN88US=> M3TSVXNCVkeHUh?=
LS-513 MmTSS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXnJR|UxRTBwMki3O|Mh|ryP MYrTRW5ITVJ?
NCI-H630 M{T1N2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{DnNWlEPTB;MD6yPVM4PiEQvF2= NGjRUopUSU6JRWK=
L-428 NYDVd4h{T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3TTeGlEPTB;MD6yPVg5OyEQvF2= NWLmXpdCW0GQR1XS
UM-UC-3 NVGx[lJJT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NX\WUoRzUUN3ME2wMlMyOjlzIN88US=> NGnEZ3FUSU6JRWK=
NCI-H1838 MlrjS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3rifmlEPTB;MD6zNVc5PCEQvF2= MYTTRW5ITVJ?
HEL NGTt[|lIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4DWNmlEPTB;MD6zNlI1KM7:TR?= Mlz4V2FPT0WU
OCI-AML2 NHrQOlNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MlfGTWM2OD1yLkOyNlk5KM7:TR?= MVjTRW5ITVJ?
A3-KAW NWLBe4dvT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmTKTWM2OD1yLkOzOFc4KM7:TR?= NE\GcnhUSU6JRWK=
IGROV-1 NX24XIJPT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVT4bI5GUUN3ME2wMlM{PzV3IN88US=> M4mzWXNCVkeHUh?=
Mo-T NHvhTYlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MljJTWM2OD1yLkOzPFU{KM7:TR?= MWDTRW5ITVJ?
HDLM-2 MVjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M37YdGlEPTB;MD6zN|kh|ryP MnXHV2FPT0WU
HCC1569 M2n4e2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXHJR|UxRTBwM{SzNFkh|ryP NV30fnU3W0GQR1XS
COLO-678 MWTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MlnwTWM2OD1yLkO3NFAzKM7:TR?= MXjTRW5ITVJ?
COR-L105 NUnncFZFT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M13MTmlEPTB;MD6zO|k{KM7:TR?= M1H5TnNCVkeHUh?=
SK-MEL-24 MVLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MVjJR|UxRTBwM{izPFIh|ryP M1H2bHNCVkeHUh?=
COLO-320-HSR NETKXFVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Moe3TWM2OD1yLkSzPVc3KM7:TR?= M4rGd3NCVkeHUh?=
C8166 NIrHVGFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MlLTTWM2OD1yLkS5NFI{KM7:TR?= MY\TRW5ITVJ?
COLO-679 MojIS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NV2wSXh3UUN3ME2wMlYzOTd{IN88US=> M{DhU3NCVkeHUh?=
TE-12 M2fOOmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHHheWxKSzVyPUCuOlU{QTRizszN M2rEdnNCVkeHUh?=
HAL-01 NH63Z4VIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MULJR|UxRTBwNk[yNkDPxE1? NH;2[mFUSU6JRWK=
H-EMC-SS MlvPS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NUjIdG0xUUN3ME2wMlcxPTR4IN88US=> M2jOb3NCVkeHUh?=
SNU-449 NXHaR3JjT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1ThS2lEPTB;MD63Nlc1QCEQvF2= NGi2T3dUSU6JRWK=
C32 NIq0PWZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWnYdoRrUUN3ME2wMlc1OTF{IN88US=> MkW0V2FPT0WU
K-562 M{jNemdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXjJR|UxRTBwN{ewNlQh|ryP NUPPNotEW0GQR1XS
DJM-1 MkTKS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVrmeYk4UUN3ME2wMlc5PzhzIN88US=> NWfmRpZ3W0GQR1XS
RCC10RGB M2\ZUGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2nmWWlEPTB;MD63PVE5OyEQvF2= NGW2NYtUSU6JRWK=
CAL-85-1 MmXUS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHfOcJhKSzVyPUCuPVA4KM7:TR?= MXLTRW5ITVJ?
NY MmG3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mnq1TWM2OD1yLkmzN|UzKM7:TR?= M3jYO3NCVkeHUh?=
NCI-H1993 NHjEcnBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MUjJR|UxRTFwMUmyPFkh|ryP MUXTRW5ITVJ?
SK-OV-3 NITCNlJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M{DyT2lEPTB;MT6yNlA5QSEQvF2= NYrqWoZrW0GQR1XS

... Click to View More Cell Line Experimental Data

Assay
Methods Test Index PMID
Western blot
PIM1; 

PubMed: 18426800     


Cells were treated with 100 nm docetaxel for the indicated times. PIM1 and β-ACTIN proteins were analyzed by immunoblot analysis. One of three similar blots is shown. Ratio, ratio of PIM1/β-ACTIN from pooled densitometry data from three separate experimen䲧疝Ỵ疞㧀疜膉痘 瘿뾠ՂᾰƌՂĀ 㺣痖帉痖Ѐ瑖堘𢡄빢᎒ՂĀ鑸᎒彿堙奋堙巫堙᎒ﻺ᎒彿堙ﻮ᎒塚堙ﻺ᎒ꍈ堞빢᎒學堙漸堞圔堙빢᎒圞堙圭堙𢡄玚Wᾰƌ ᾰƌ戤瘯Ɖ⟸෕䐺痖暼瘿⟸෕ᾰƌ

cyclin B; 

PubMed: 18426800     


Immunoblot analysis of cyclin B1 and PIM1 expression after docetaxel 10 nm (left) or 100 nm (right) treatment at various time points.

pSTAT3 / STAT3 ; 

PubMed: 18426800     


Immunoblots of RWPE-2 cells treated with 100 nm docetaxel for the indicated time.

p-p53 / p53; 

PubMed: 22996738     


C4-2 cells were treated with 5 nM docetaxel, the whole cell lysates were collected at different time points and subjected to Western blot.

18426800 22996738
Immunofluorescence
α-tubulin; 

PubMed: 27177833     


Noscapine has no effect on gross microtubule polymerization state but noscapine pre-sensitization followed by docetaxel treatment stabilizes microtubules, hence inhibits cell proliferation. TNBC cells were treated with noscapine (4 µM) or docetaxel (0.4 µ䲧疝Ỵ疞㧀疜膉痘 瘿⟸෕ᾰƌ෕Ð 㺣痖帉痖Ѐ瑖堘𢡄빢᎒෕Ð鑸᎒彿堙奋堙巫堙᎒ﻺ᎒彿堙ﻮ᎒塚堙ﻺ᎒ꍈ堞빢᎒學堙漸堞圔堙빢᎒圞堙圭堙𢡄玚Wᾰƌ ᾰƌ戤瘯Ɖ뾠Ղ䐺痖暼瘿뾠Ղᾰƌ 뾠ՂÐ㺣痖뾠Ղ€𢡄뾤Ղ€䀷痗뾤Ղ౴뾤Ղ㵶痗뾤Ղ뺖᎒泌Itemセ᎒Count﫨呂뿔Ղ猴፲뾤Ղ፲씢痗猸፲髸莤䥷堙᎒セ᎒�堞ﻮ᎒፲露𢡄堚Ҕ齃礤v�堞ﻮ᎒猢Wセ᎒䨼Ą鹿齃殺獸W戀醙

cleaved PARP / cleaved caspase-3; 

PubMed: 21087597     


Immunofluorescence images of PC-3 cells treated with the docetaxel and EM011 schedule treatment. Cells were pretreated with docetaxel for 12 h before addition of EM011 and were fixed at 48 h post docetaxel treatment compared to treatment with EM011 (10 μM䲧疝Ỵ疞㧀疜膉痘 瘿⟸෕ᾰƌ෕Ð 㺣痖帉痖Ѐ瑖堘𢡄빢᎒෕Ð鑸᎒彿堙奋堙巫堙᎒ﻺ᎒彿堙ﻮ᎒塚堙ﻺ᎒ꍈ堞빢᎒學堙漸堞圔堙빢᎒圞堙圭堙𢡄玚Wᾰƌ ᾰƌ戤瘯Ɖ�෋䐺痖暼瘿�෋ᾰƌ �෋à

Acetylated tubulin ; 

PubMed: 18426800     


Immunofluorescence of acetylated tubulin in cells treated with DMSO, 30 nM laulimalide and 30 nM docetaxel for 2.5 h. Tubulin shown in green and DAPI in blue, and the white arrow indicates microtubule bundling. Scale bar represents 10 μm.

SQSTM1 / LAMP1; 

PubMed: 29795139     


AGS cells were treated with docetaxel (10 nM) for 12 h. After immunostaining with SQSTM1 (Alexa Fluor 488, green) and LAMP1 (Alexa Fluor 594, red), cells were examined by fluorescence microscopy (scale bar 20 μm). The colocalization of SQSTM1and LAMP1 was䲧疝Ỵ疞㧀疜膉痘 瘿�෋ᾰƌ෋à 㺣痖帉痖Ѐ

27177833 21087597 18426800 29795139
Growth inhibition assay
Cell viability ; 

PubMed: 22996738     


Docetaxel inhibits the growth of LNCaP, C4-2, DU145, and PC3 prostate cancer cells. Cells were plated in 12-well plates and treated with different concentrations of docetaxel. The cell number was counted after 24 hr. 

22996738
In vivo Docetaxel (33 mg/kg/dose, given i.v. every 4 days for 3 injections) results in a tumor growth delay of 19.3 days in M2OL2 colon xenografts. Docetaxel also shows great antitumor activities in MX-1, SK-MEL-2, LX-1 and OVCAR-3 xenografts. Docetaxel inhibits the angiogenic response to fibroblast growth factor 2 with IC 50 of 5.4 mg/kg when injected twice weekly over a 14-day period, and angiogenesis is completely blocked in mice that receives 10 mg/kg Docetaxel. Docetaxel has selectivity for endothelial cell migration and/or microvessel formation because infiltration of inflammatory cells into the Matrigel plug is much less sensitive to inhibition by Docetaxel. [7]

Protocol

Cell Research:[5]
+ Expand
  • Cell lines: Human gastric cancer cell lines MKN-28
  • Concentrations: 6 nM
  • Incubation Time: 3 days
  • Method: 2000 cells in 180 μL of medium are seeded in a 96-well plate, and 20 μL of drug solution is simultaneously added in triplicate to each well. The plate is incubated for 3 days at 37°C in a humidified atmosphere of 5% CO2. On day 3, 25 μL of MTT reagent is added to each well. After 4 h of incubation, the medium is removed by aspiration. 0.2 mL of dimethylsulphoxide (DMSO) is added to each well and thoroughly mixed by using a mechanical plate mixer to dissolve the resulting MTT-formazan crystals. Absorbance at 540 nm (OD) is measured by a reader.
    (Only for Reference)
Animal Research:[6]
+ Expand
  • Animal Models: Human colon carcinomas xenografts CX-1
  • Formulation: 50 mg/mL stock solution in ethanol by adding an equal volume of polysorbate 80 and diluting with 5% dextrose in water to the final volume
  • Dosages: 33 mg/kg
  • Administration: i.v. every 4 days for 3 injections
    (Only for Reference)

Solubility (25°C)

In vitro DMSO 100 mg/mL (123.78 mM)
Ethanol 53 mg/mL warmed (65.6 mM)
Water Insoluble
In vivo Add solvents to the product individually and in order(Data is from Selleck tests instead of citations):
5% DMSO+30% PEG 300+5% Tween 80+ddH2O
For best results, use promptly after mixing.
2mg/mL

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 807.88
Formula

C43H53NO14

CAS No. 114977-28-5
Storage powder
in solvent
Synonyms RP56976, NSC 628503

Bio Calculators

Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

  • Mass
    Concentration
    Volume
    Molecular Weight

*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

  • C1
    V1
    C2
    V2

* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).

The Serial Dilution Calculator Equation

  • Serial Dilutions

  • Computed Result

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):
Molecular Weight Calculator

Molecular Weight Calculator

Enter the chemical formula of a compound to calculate its molar mass and elemental composition:

Total Molecular Weight: g/mol

Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2

Instructions to calculate molar mass (molecular weight) of a chemical compound:

To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.

Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Clinical Trial Information

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT03863483 Not yet recruiting Nonsquamous Non-Small Cell Lung Cancer Xin-Hua Xu|China Three Gorges University Yichang China July 1 2019 Phase 2
NCT03863483 Not yet recruiting Nonsquamous Non-Small Cell Lung Cancer Xin-Hua Xu|China Three Gorges University Yichang China July 1 2019 Phase 2
NCT03830411 Not yet recruiting Nonsquamous Non-Small Cell Lung Cancer Xin-Hua Xu|China Three Gorges University Yichang China June 1 2019 Phase 2
NCT03830411 Not yet recruiting Nonsquamous Non-Small Cell Lung Cancer Xin-Hua Xu|China Three Gorges University Yichang China June 1 2019 Phase 2
NCT03834506 Not yet recruiting Prostatic Neoplasms Merck Sharp & Dohme Corp. May 15 2019 Phase 3
NCT03609047 Not yet recruiting Breast Cancer Stage II|Breast Cancer Stage III European Organisation for Research and Treatment of Cancer - EORTC|Pfizer May 7 2019 Phase 2

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3

If you have any other enquiries, please leave a message.

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