1V209 (TLR7 agonist T7)

For research use only.

Catalog No.S0078 Synonyms: T7

1V209 (TLR7 agonist T7) Chemical Structure

CAS No. 1062444-54-5

1V209 (T7, TLR7 agonist T7) is an agonist of Toll-like receptor 7 (TLR7) with anti-tumor effects. 1V209 can be used as vaccine adjuvants, enhances antigen specific humoral and cellular immune responses.

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Biological Activity

Description 1V209 (T7, TLR7 agonist T7) is an agonist of Toll-like receptor 7 (TLR7) with anti-tumor effects. 1V209 can be used as vaccine adjuvants, enhances antigen specific humoral and cellular immune responses.
Targets
TLR7 [1]
()

Protocol

Solubility (25°C)

In vitro DMSO 72 mg/mL (200.36 mM)
Water Insoluble
Ethanol Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 359.34
Formula
C16H17N5O5
CAS No. 1062444-54-5
Storage powder
in solvent
Synonyms T7
Smiles COCCOC1=NC(=C2C(=N1)N(C(=O)N2)CC3=CC=C(C=C3)C(=O)O)N

In vivo Formulation Calculator (Clear solution)

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The Serial Dilution Calculator Equation

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Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

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Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT04616586 Terminated Drug: Siltuximab|Other: Normal Saline Acute Respiratory Distress Syndrome|Lung Diseases|Pneumonia|Respiratory Tract Infections|Respiratory Tract Disease EusaPharma (UK) Limited|Syneos Health November 13 2020 Phase 3
NCT04779424 Active not recruiting Other: POCT SARS-CoV-2|COVID-19 Universiteit Antwerpen|Sciensano|University of Liege November 15 2020 --

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID