1V209 (TLR7 agonist T7)

Catalog No.S0078 Synonyms: T7

For research use only.

1V209 (T7, TLR7 agonist T7) is an agonist of Toll-like receptor 7 (TLR7) with anti-tumor effects. 1V209 can be used as vaccine adjuvants, enhances antigen specific humoral and cellular immune responses.

1V209 (TLR7 agonist T7) Chemical Structure

CAS No. 1062444-54-5

Purity & Quality Control

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Biological Activity

Description 1V209 (T7, TLR7 agonist T7) is an agonist of Toll-like receptor 7 (TLR7) with anti-tumor effects. 1V209 can be used as vaccine adjuvants, enhances antigen specific humoral and cellular immune responses.
Targets
TLR7 [1]

Protocol (from reference)

Solubility (25°C)

In vitro

Chemical Information

Molecular Weight 359.34
Formula
C16H17N5O5
CAS No. 1062444-54-5
Storage 3 years -20°C powder
2 years -80°C in solvent
Smiles COCCOC1=NC(=C2C(=N1)N(C(=O)N2)CC3=CC=C(C=C3)C(=O)O)N

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Clinical Trial Information

NCT Number Recruitment Interventions Conditions Sponsor/Collaborators Start Date Phases
NCT05396690 Not yet recruiting Drug: Remimazolam Injection [Byfavo]|Drug: Sevoflurane Coronary Artery Bypass Surgery Ajou University School of Medicine June 15 2022 Not Applicable
NCT04616586 Terminated Drug: Siltuximab|Other: Normal Saline Acute Respiratory Distress Syndrome|Lung Diseases|Pneumonia|Respiratory Tract Infections|Respiratory Tract Disease EusaPharma (UK) Limited|Syneos Health November 13 2020 Phase 3

(data from https://clinicaltrials.gov, updated on 2022-08-01)

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