TLR4-IN-C34

For research use only.

Catalog No.S0822 Synonyms: TLR4-C34, C34, TLR4-C34-IN

TLR4-IN-C34 Chemical Structure

CAS No. 40592-88-9

TLR4-IN-C34 (TLR4-C34, C34, TLR4-C34-IN) is a potent and selective antagonist of Toll-like receptor 4 (TLR4). TLR4-IN-C34 reduces systemic inflammation in mouse models of endotoxemia and necrotizing enterocolitis.

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Biological Activity

Description TLR4-IN-C34 (TLR4-C34, C34, TLR4-C34-IN) is a potent and selective antagonist of Toll-like receptor 4 (TLR4). TLR4-IN-C34 reduces systemic inflammation in mouse models of endotoxemia and necrotizing enterocolitis.
Targets
TLR4 [1]
()

Protocol

Solubility (25°C)

In vitro DMSO 78 mg/mL (200.3 mM)
Water 78 mg/mL (200.3 mM)
Ethanol ''78 mg/mL

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 389.40
Formula

C17H27NO9

CAS No. 40592-88-9
Storage powder
in solvent
Synonyms TLR4-C34, C34, TLR4-C34-IN
Smiles CC(C)OC1C(C(C(C(O1)COC(=O)C)OC(=O)C)OC(=O)C)NC(=O)C

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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID